Liver Disease and Other Systemic Diseases

Condition(s) studied

Study summary

Examine the association of chronic liver diseases (including hepatitis B, hepatitis C, alcoholic liver disease, fatty liver, liver cirrhosis, and hepatocellular carcinoma) with other systemic diseases by retrospectively analyzing the data from the Hospital Database of Buddhist Tzu Chi Medical Foundation.

Eligibility

Primary outcome measure(s)

• The incidence of a new diagnosis of hepatocellular carcinoma (HCC) — From the date of enrollment until the date of first documented diagnosis of HCC, assessed up to 120 months.
  The new diagnosis of HCC is assessed every 3 months by abdominal sonography, and every 6 months with tumor markers (e.g. AFP), and confirmed by dynamic CT or MRI or pathological examination.
• The incidence of a new diagnosis of any event of liver cirrhosis complications — From the date of enrollment until the date of first documented any event of liver cirrhosis complications, or date of death from any cause, whichever came first, assessed up to 120 months.
  Liver cirrhosis complications include ascites, esophageal or gastric varices bleeding, hepatorenal syndrome, spontaneous bacterial peritonitis, hepatic encephalopathy, hepatic pulmonary syndrome, liver failure (Child-Pugh score B or C), or liver transplant, that are assessed every 3 months clinically. A new diagnosis of any event of liver cirrhosis complications is a new documented any of the above liver cirrhosis complications, whichever came first.

Trial sites (1)

More Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation trials in Taiwan

Other trials for the same condition