Hypnosis on Breathlessness Mastery in Patients With Persistent Dyspnea

NCT07173348 · tracked via the Priya Life Science Switzerland tracker

Sponsor

University Hospital, Geneva

Phase

Not applicable

Started

2026-04-01

Last updated

2026-06-08

Condition(s) studied

Cancer (With or Without Metastasis)Interstitial Lung Disease (ILD)Chronic Heart Failure (CHF)COPDDyspnea

Investigational drug(s) / intervention(s)

Hypnosis

Hypnosis: Participants will undergo three 15-minute individual hypnosis intervention, conducted by a trained hypnotherapist, with a two-week interval between each session. A guide for the session has been developed by two experimented hypnotherapists specifically for this intervention and will be used for all sessions. A total of 3 hypnosis session will be realized.

Study summary

Persistent dyspnea is a debilitating symptom, that is common and difficult to treat. This symptom is found in many different diseases including chronic obstructive pulmonary disease (COPD), interstitial lung disease (ILD), chronic heart failure (CHF), and metastatic cancer. Dyspnea is associated with many other symptoms, including anxiety, depression, and fatigue and is responsible for a significant reduction in quality of life. To date, only opiates are recommended for the pharmacological treatment of persistent dyspnea.

The effectiveness of hypnosis is well known in the treatment of anxiety and delivered to patients suffering from chronic dyspnea for this reason. One randomised controlled study has shown that a single 20-minute mindfulness sessions could significantly reduce general symptom burden and have a significant impact on anxiety and depression in palliative care patients. Furthermore, the intervention had no negative side effects.

Our aim is to evaluate the effectiveness of three hypnosis sessions on breathlessness mastery in patients with persistent dyspnea, using as a primary outcome the mastery domain of a validated tool, the Chronic Respiratory Questionnaire (CRQ).

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Patients aged ≥ 18 years and * Primary diagnosis of metastatic cancer, COPD stage at least B or E, ILD, or CHF and * Dyspnea stage NYHA ≥ II or mMRC ≥ 2 Exclusion Criteria: * Have had hypnosis treatment in the last 12 months * Have an estimated life expectancy of less than 6 months * Have participated in pulmonary rehabilitation in the last 6 months * Have been hospitalised in the last month (30 days) * Are unable to come to the hospital for 3 outpatient consultations (1 every two weeks) * Have a condition that would interfere with their ability to respond to the questionnaires (i.e. cognitive impairment, hearing impairment, etc.) * Are not eligible for a hypnosis session due to a psychiatric disorder

Primary outcome measure(s)

Chronic Respiratory Questionnaire (CRQ): sub scale mastery — From enrollment to the end of the intervention at 6 weeks.
The CRQ is a validated 20-item health-related quality of life questionnaire in which experiences are rated on seven-point scales ranging from 1 (maximum impairment) to 7 (no impairment). The CRQ mastery is a domain of the CRQ which comprises four questions with a range of scores also ranging from 1 to 7

Trial sites (1)

Facility	City	Region	Status
Geneva University Hospitals	Geneva	Canton of Geneva	Recruiting

More University Hospital, Geneva trials in Switzerland

Genetic Risks for Childhood Cancer Complications in Switzerland Recruiting

Incremental Diagnostic Value of Tau-PET With [18F]RO948 vs Amyloid-PET in Patients With Cognitive Impairment Recruiting

Anhydroglucitol in Children With Type 1 Diabetes Recruiting

@neurIST : Intregrated Biomedical Informatics for the Management of Cerebral Aneurysms Recruiting

Hyperbaric Oxygen Therapy to Improve Autologous Fat Graft Intake in Irradiated Breast Recruiting

Other trials for the same condition

The Acute Cardiorespiratory Response to Blood-flow Restricted Versus Traditional Exercise Training Regimens (CaRe BFR) Recruiting

Emotional-distress-based Integrated Care Programme in Patients With Stable COPD Active, not recruiting

Basics in Acute Shortness of Breath EvaLuation (BASEL V) Study Active, not recruiting

Robotic-Assisted Versus Conventional Bronchoscopy for Cryobiopsy in the Diagnosis of Interstitial Lung Disease Recruiting

Supporting Patients Starting New Medicines: Evaluating the myCare Start Service in Switzerland Starting soon

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07173348 on ClinicalTrials.gov ↗ ← All trials in Switzerland