Genetic Variants and Postoperative Pain

NCT03489499 · tracked via the Priya Life Science Switzerland tracker

Sponsor

Insel Gruppe AG, University Hospital Bern

Phase

Observational

Started

2011-01-02

Last updated

2026-01-07

Condition(s) studied

Postoperative PainAnalgesiaSurgical Procedure, Operative

Study summary

Prospective observational study to analyse patients' pain related outcome after surgery and ist association to genetic variants and non-genetic variables.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Accepted

Inclusion Criteria: * 18 years and older * Written informed consent * Elective surgery * Patients' ability to understand the purpose of the study Exclusion Criteria * No informed consent * Cognitive impairment

Primary outcome measure(s)

Pain related impairment after surgery and its association to genetic and non-genetic variables — day of surgery up to 1 year after surgery
Measured by the International Pain Outcomes Questionnaire, the Brief Pain Inventory (BPI): Numeric rating scale for pain intensities, affective and physical interference; Composite score = pain interference total scores (PITS scale 0-10) resulting in no interference (PITS=0), mild interference (PITS \>0 and \<2), moderate interference (PITS 2-5) and severe interference (PITS \>5)

Trial sites (1)

Facility	City	Region	Status
Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern	Bern	Switzerland	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT03489499 on ClinicalTrials.gov ↗ ← All trials in Switzerland