Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 7 of 7)

Condition(s) studied

Investigational drug(s) / intervention(s)

Visible light exposure: Subjects will be exposed to visible colored light for 45 minutes. The visible light will be generated by red-green-blue light emitting diodes light cans.

Study summary

NOTE: This is the seventh of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674. This sub-study includes 50 participants and 8 arms, in total 350 participants will be assessed in all 7 sub-studies.

General study information: This is a randomized, cross-over, quantitative study, which investigates physiological variables, mood, and affect of healthy participants in response to colored light exposure. The Participants take part in 5-8 arms and are exposed to colored light only, or are additionally asked to solve cognitive tasks during the colored light exposure. Primary aim is to measure the change in several physiological variables, mood, and affect during colored light exposure of 15 or 45 minutes. The risk for the participants is negligible and comparable to the risk during daily life.

Eligibility

Primary outcome measure(s)

• Change in cerebral tissue oxygen saturation during colored light exposure compared with a baseline and a recovery period — 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
• Change in cerebral hemoglobin concentration during colored light exposure compared with a baseline and a recovery period — 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
• Change in variables of the heart rate variability during colored light exposure compared with a baseline and a recovery period — 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
• Change in variables of the electro-dermal activity during colored light exposure compared with a baseline and a recovery period — 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
• Change of the blood pressure during colored light exposure compared with a baseline and a recovery period — 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
• Change of the partial pressure of carbon dioxide during colored light exposure compared with a baseline and a recovery period — 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
• Change of the respiration rate during colored light exposure compared with a baseline and a recovery period — 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
• Change of the heart rate during colored light exposure compared with a baseline and a recovery period — 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
• Change of the pulse-respiratory quotient during colored light exposure compared with a baseline and a recovery period — 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
  The pulse-respiratory quotient will be calculated as heart rate divided by the respiration rate.
• Change of the arterial oxygen saturation during colored light exposure compared with a baseline and a recovery period — 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)

Trial sites (1)

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