Ireland
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Starting soon Observational

The Örebro Severe Traumatic Brain Injury Registry

NCT07398274 · tracked via the Priya Life Science Sweden tracker
Sponsor
András Zoltán Buki
Phase
Observational
Started
2026-02-08
Last updated
2026-02-09

Condition(s) studied

Severe Traumatic Brain InjurySevere Brain InjuryIschemic StrokeIntracerebral Hemorrhage

Study summary

Traumatic brain injury and other severe brain injuries requiring neurointensive care are associated with high mortality, long-term disability and substantial societal burden. Despite advances in critical care, outcomes after severe brain injury remain difficult to predict and secondary brain injury plays a major role in determining prognosis.

The Örebro Severe Brain Injury Database (ÖrSBID) is a prospective observational registry that aims to systematically collect detailed clinical, physiological, imaging and biological data from adult patients with severe brain injury requiring care at the neurointesive care unit or neurointermediate care unit at Örebro University Hospital.

The purpose of the registry is to enable deep phenotyping of severe brain injury, improve understanding of secondary injury mechanisms, support outcome prediction and provide a platform for longitudinal follow-up and future research. No experimental interventions are performed as part of the study.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age \> 16 years * Severe traumatic brain injury or other severe brain injury requiring neurointensive or neurointermediate care * Admission to Örebro University Hospital Exclusion Criteria: * Age \< 16 years \< 90 years * Non-survivable brain injury * Patients not requiring neurointensive or neurointermediate care * Declinced consent by patient or legal representative

Primary outcome measure(s)

  • Functional outcome at 12 months — Up to 12 months after injury
    Functional outcome assessed up to 12 months after injury using clinical outcome measures and registry-based follow-up data

Trial sites (1)

FacilityCityRegionStatus
Örebro University Hospital Örebro Örebro County
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07398274 on ClinicalTrials.gov ↗ ← All trials in Sweden