Exercise-induced Cardioversion in Persistent Atrial Fibrillation

Condition(s) studied

Investigational drug(s) / intervention(s)

Bicycle ergometer excercise: Patients will undergo a symptom-limited ergometer cycling test under medical supervision. If the atrial fibrillation is not converted to sinus rhythm during the exercise test, the patients will be electrically converted.

Standard care with electrical cardioversion: Standard care with planned electrical cardioversion without exercise intervention.

Study summary

This study aims to to evaluate the feasibility of conducting a larger randomized controlled trial (RCT) to assess whether an exercise stress test on an ergometer bicycle could induce sinus rhythm in patients with persistent AF scheduled for electrical cardioversion and if this intervention (regardless of rhythm conversion) could improve health-related quality of life in these patients.

Eligibility

Primary outcome measure(s)

• Feasibility of the pilot study - Recruitment rate — Day 1
  Number of patients asked to participate in the study
• Feasibility of the pilot study - Consent rate — Day 1
  Number of patients giving written consent to participate in the study
• Feasibility of the pilot study - Participant fidelity — From enrollment to the end of assessments, an average of 2 months
  Ability of participants to comply with the intervention protocol.
• Feasibility of the pilot study - Study retention — Through study completion, an average of 6 months
  Participants dropout rates.
• Feasibility of the pilot study - Adverse events — Through study completion, an average of 6 months
  Side effects and adverse events during the study

Trial sites (1)

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