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Clinical Trials in Sweden / NCT06811948
Starting soon Observational

Sleep-Disordered Breathing in the Acute Phase After Stroke and Neuropsychiatric Outcomes

NCT06811948 · tracked via the Priya Life Science Sweden tracker
Sponsor
Blekinge County Council Hospital
Phase
Observational
Started
2025-02-20
Last updated
2025-02-06

Condition(s) studied

StrokeFatigue SymptomObstructive Sleep ApneaSleep Disordered Breathing (SDB)

Study summary

In people who have had a stroke or a transient ischemic attack (TIA), it is common to have problems with breathing patterns during sleep, particularly a condition called obstructive sleep apnea. Another common long-term problem after a stroke is post-stroke fatigue, which affects function and quality of life after stroke. There is currently no clearly effective treatment for post-stroke fatigue. We are investigating whether there might be a connection between sleep-related breathing disturbances, and the risk of developing long-term post-stroke fatigue

The project is being conducted at Blekingesjukhuset Karlskrona, and inpatients with stroke are asked to participate. Participants are equipped with a sleep analysis pad under the mattress that measures breathing patterns during the night, as well as a wrist-worn device that measures oxygen saturation in the blood. Participants are also asked about their functional level in daily life and any symptoms of obstructive sleep apnea. One year after the stroke, participants are invited for a follow-up visit where we ask about post-stroke fatigue, depressive symptoms, and treatment and investigations related to the stroke.

We will then investigate the relationship between sleep-related breathing disturbances, measured early after stroke, and the risk of significant fatigue after the stroke. This could lead to future studies with treatment trials for obstructive sleep apnea in certain individuals with post-stroke fatigue. The study could also lead to potentially increased awareness that these conditions might be connected, which could result in a higher likelihood of detecting treatable obstructive sleep apnea in certain subgroups after stroke.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age \>18 years * Stroke according to WHO definition (31) (ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage) * TIA with MRI-verified lesions corresponding to symptoms * Informed consent to participate Exclusion Criteria: * Traumatic stroke * Tumor-associated bleeding * Expected survival \<3 months * Unconsciousness (RLS \>3)

Primary outcome measure(s)

  • Fatigue Assessment Scale — 1 year follow-up
    Measurement of post-stroke fatigue at 1 year follow-up.

Trial sites (1)

FacilityCityRegionStatus
Blekinge Hospital Karlskrona Blekinge County

More Blekinge County Council Hospital trials in Sweden

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Other trials for the same condition

Stroke Rehabilitation Using Extended Reality. Starting soon
The EXOPULSE Study - a Database for Routine Follow-up of Clinical Outcomes Recruiting
Stroke Prophylaxis With Apixaban in Chronic Kidney Disease Stage 5 Patients With Atrial Fibrillation Recruiting
Internet Delivered Cognitive Rehabilitation for Mild Cognitive Impairments Enrolling by invitation
Evaluation of the Ronnie Gardiner Method in Individuals With Stroke in Late Phase of Recovery Active, not recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06811948 on ClinicalTrials.gov ↗ ← All trials in Sweden