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Clinical Trials in Sweden / NCT06594107
Recruiting Observational

Factors for the Onset and Course of Axial Spondylitis

NCT06594107 · tracked via the Priya Life Science Sweden tracker
Sponsor
Karolinska Institutet
Phase
Observational
Started
2022-09-01
Last updated
2024-09-24

Condition(s) studied

Axial Spondyloarthritis

Study summary

In a research project, investigators want to study the course of the disease of axial spondylitis: the causes of disease onset, prognosis, and treatment effects. The goal is to improve treatment and in the long run also prevention of the disease. The project has a focus on the body\'s own substance prostaglandin, and its proinflammatory role in spondylitis, but also other substances may be analyzed in blood and urine samples.

The purpose of the research project is include newly diagnosed treatment-naive patients with axial spondyloarthritis, to follow them after 1 and 2 years after treatment start, to collect clinical data, questionnaires, blood and urinsamples to find blood or urine markers that can be used for precision therapy of axial spondylitis.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * newly diagnosed patients with axial spondyloarthritis * treatment-naive * 18 years of age or older * Swedish-speaking * Able to give informed consent Exclusion Criteria: * DMARD treatment, * ongoing infection * ongoing malignancy

Primary outcome measure(s)

  • Prostaglandin levels — 2 years
    Investigators measure prostaglandin levels in treatment-naïve patients at baseline, and then after therapy start after 1 and 2 years.

Trial sites (2)

FacilityCityRegionStatus
Karolinska University Hospital Huddinge Stockholm County Recruiting
Center for Rheumatology Stockholm Stockholm Stockholm County Recruiting

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Other trials for the same condition

High-intensity Training in Patients With Spondyloarthritis: a Randomized Controlled Trial Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06594107 on ClinicalTrials.gov ↗ ← All trials in Sweden