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Clinical Trials in Sweden / NCT06253754
Recruiting Observational

Pathophysiological Mechanisms and Implication of Treatment in Postural Puncture Headache

NCT06253754 · tracked via the Priya Life Science Sweden tracker
Sponsor
Umeå University
Phase
Observational
Started
2024-01-30
Last updated
2024-02-12

Condition(s) studied

Post-Dural Puncture Headache

Investigational drug(s) / intervention(s)

MRI examination

MRI examination: All included subjects will be examined with MRI

Study summary

To improve treatment for post dural puncture headache, its pathophysiology needs to be explored. Dural puncture alters CNS dynamics; using advanced MRI, we aim to investigate PDPHs pathophysiology explained by brain movement, cerebral blood flow, CSF dynamics and the effect of epidural blood patch.

Eligibility

Sex
ALL
Min age
20 Years
Max age
40 Years
Healthy volunteers
No
Inclusion Criteria: Postural puncture headache Age 20-40 Exclusion Criteria: * Other central neurological disorders except the actual * Acute medical condition * Pregnancy * Pacemaker, or other medical implants that are not MRI-compatible * Invasive procedures on the central nervous system or surgery on the spine or brain in the last 12 months.

Primary outcome measure(s)

  • Changes in cerebral dynamics with MRI — After 3 months
    Cerebral blood flow and CSF

Trial sites (1)

FacilityCityRegionStatus
Umeå University Hospital Umeå Västerbotten County Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06253754 on ClinicalTrials.gov ↗ ← All trials in Sweden