Opioid UseOpioid Use DisorderAlcohol Use DisorderPain, Chronic
Investigational drug(s) / intervention(s)
Current Opioid Misuse Measure (COMM)-SWEOral fluid drug testPEThASI-SRAUDITDUDITBrief Pain Inventory - BPIPatient Global Impression of Change PGICGAD-7Patient Health questionnaire (PHQ9)DBS - cannabis testSample of Blood for later DNA and immunological analysis in future studies
Current Opioid Misuse Measure (COMM)-SWE: Patients in test group should fulfill the the COMM and the battery of validation forms as well as leave the oral fluid for illicit drugs test and whole blod for phosphatidylethanol test.
Oral fluid drug test: Oral fluid sampling to detect drugs. Analysis with LC-HRMS
PETh: Alcohol use detection
ASI-SR: Cross-validation form
AUDIT: Cross-validation form
DUDIT: Cross-validation form
Brief Pain Inventory - BPI: Cross-validation form
Patient Global Impression of Change PGIC: Cross-validation form
GAD-7: Cross-validation form
Patient Health questionnaire (PHQ9): Cross-validation form
DBS - cannabis test: cross-validation form
Sample of Blood for later DNA and immunological analysis in future studies: sample collection for future studies
Study summary
The goal of this observational study is to translate the COMM (Current opinion misuse measure) form and validate it using the ASI-SR (Addiction severity score-self report)in a Swedish population of pain patients treated with opioids. The secondary aim is to investigate acceptability of the instrument in a Swedish population of pain patients with long-term opioid treatment (LOT).
The tertiary aim is to investigate the prevalence of alcohol and illicit substance use in a Swedish population of pain patients with LOT.
Eligibility
Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria:
Intervention group:
* Patients with long-term, non-cancer-related pain (\>3 months) at least 3 days a week
* opioid treatment for at least 1 month during last 6 months
* age 18-75 years
* fluent in spoken and written Swedish.
Control group:
* Patients with long-term, non-cancer-related pain (\>3 months) at least 3 days a week
* no opioid treatment at inclusion and during last 3 months
* age 18-75 years
* fluent in spoken and written Swedish
Exclusion Criteria:
* ongoing diseases or conditions that prevents the patient from completing to the study according to the doctor's assessment
* serious cognitive disorder that makes answering the questions impossible. - - ongoing or treated cancer in the last 10 years
* Insufficient knowledge of Swedish
Primary outcome measure(s)
COMM - Current opioid misuse version Swedish version — Baseline COMM is based on 17 questions, all of which are answered on a 5-point Likert scale.
As the original COMM instrument has identified 5 categories of questions, each area will be assessed against the following instruments:
1. Symptoms and signs of drug abuse (question 1) - AUDIT, DUDIT, ASI-SR, drug and alcohol test
2. Emotional and psychiatric problems (questions 2,5,7,8,13) - ASI-SR, GAD-7, PHQ9
3. Visitor characteristics/patterns (questions 3,12,17) - medical record data
4. Occurrence of untrue statement (doubt/lie/untruth) and drug use (questions 4,6,9,10,11) - medical record data, drug and alcohol tests
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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