Long-term Surgical Treatment Outcome of Peri-implantitis Lesions

Condition(s) studied

Study summary

The surgical treatment outcome of patients that have been or are consecutively treated at the University of Malmö, at Blekinge hospital, and at the Dental Clinic of the Sigmund Freud University Vienna will be evaluated on an a regular base; specifically all patients treated since 2014 and those receiving treatment in the future, will be regularly assessed, max. once per year after the 1-year control from the surgical intervention for clinical and radiographic assessment of healing. Clinical peri-implant parameters (e.g., probing pocket depth) and peri-implant sulcus fluid (PISF) are collected, and a peri-apical radiographic examination is made. Further, from 200 patients treated in the future, the inflammatory peri-implant lesion will be collected and subjected to histological, microbiological, and molecular analysis. The removal of these lesions is a standard procedure and performed in all patients independent of study participation; i.e., the lesion has anyway to be removed during surgery and if the lesions are not stored, they would be thrown.

Eligibility

Primary outcome measure(s)

• Disease resolution (Binary: yes/no) — 12 months postoperative
  Disease resolution will be defined as peri-implant probing pocket depth ≤ 5 mm and no excessive bleeding and/or suppuration on probing.
• Disease resolution (Binary: yes/no) — 24 months postoperative
  Disease resolution will be defined as peri-implant probing pocket depth ≤ 5 mm and no excessive bleeding and/or suppuration on probing.
• Disease resolution (Binary: yes/no) — 36 months postoperative
  Disease resolution will be defined as peri-implant probing pocket depth ≤ 5 mm and no excessive bleeding and/or suppuration on probing.
• Disease resolution (Binary: yes/no) — 48 months postoperative
  Disease resolution will be defined as peri-implant probing pocket depth ≤ 5 mm and no excessive bleeding and/or suppuration on probing.
• Disease resolution (Binary: yes/no) — 60 months postoperative
  Disease resolution will be defined as peri-implant probing pocket depth ≤ 5 mm and no excessive bleeding and/or suppuration on probing.
• Disease resolution (Binary: yes/no) — 72 months postoperative
  Disease resolution will be defined as peri-implant probing pocket depth ≤ 5 mm and no excessive bleeding and/or suppuration on probing.
• Disease resolution (Binary: yes/no) — 84 months postoperative
  Disease resolution will be defined as peri-implant probing pocket depth ≤ 5 mm and no excessive bleeding and/or suppuration on probing.
• Disease resolution (Binary: yes/no) — 96 months postoperative
  Disease resolution will be defined as peri-implant probing pocket depth ≤ 5 mm and no excessive bleeding and/or suppuration on probing.
• Disease resolution (Binary: yes/no) — 108 months postoperative
  Disease resolution will be defined as peri-implant probing pocket depth ≤ 5 mm and no excessive bleeding and/or suppuration on probing.
• Disease resolution (Binary: yes/no) — 120 months postoperative
  Disease resolution will be defined as peri-implant probing pocket depth ≤ 5 mm and no excessive bleeding and/or suppuration on probing.

Trial sites (3)

More Malmö University trials in Sweden

Other trials for the same condition