Transcutaneous electrical nerve stimulation (TENS): Treatment with transcutaneous electrical nerve stimulation (TENS) during 16 weeks.
Conventional analgesic treatment: Conventional analgesic treatment. Conventional analgesic treatment may include no pharmacological treatment if the patient does not use any analgesics.
Study summary
The study evaluates the effect of TENS (transcutaneous electrical nerve stimulation) as add-on treatment compared with conventional analgesic treatment in patients with endometriosis-related chronic pain. Patients with frequent pain and high pain intensity will be randomized to additional treatment with TENS or conventional treatment for 8 weeks to evaluate the acute effects of TENS treatment (n=40). Patients with endometriosis-related pain that is not frequent or without high pain intensity constitute an external control group. All patients in the study will receive TENS treatment for a total of 16 weeks, for evaluation of long-term effects of TENS treatment.
Eligibility
Sex
FEMALE
Min age
18 Years
Max age
100 Years
Healthy volunteers
No
Inclusion Criteria:
* Age ≥18 years
* Consents to participation in the study
* Verified endometriosis (by laparoscopy or ultrasound).
* Chronic endometriosis-related pain (\> 3 months), available for TENS treatment
* Functioning, stable endometriosis-specific hormonal drug therapy. The endometriosis-specific drug therapy must be unchanged for the last 3 months and no gynecological surgical procedures for the treatment of endometriosis are planned during the next 7 months (during study participation). The endometriosis-specific drug therapy does not refer to analgesic therapy for symptom relief of endometriosis-related pain.
Exclusion Criteria:
* Patient with inability to understand and use written and spoken Swedish
* Patient with pacemaker and/or ICD or other electronic implants
* Patient with impaired sensation over the painful area
* Malignant disease with an expected survival \<12 months
* Alcohol or substance abuse
* Serious untreated psychiatric illness and/or psychological condition that is the primary determinant of the patient's condition
* Participating in another intervention study with possible impact on current study outcome measures
* Patient who is using \>90 morphine equivalents/day
* Patient who is electro-acupuncture
* Pregnancy
Primary outcome measure(s)
Pain intensity — 8 weeks after randomization Pain intensity according to numeric rating scale (score from 0 to 10, where 0 is described as "no pain" and 10 as "worst pain imaginable") with regard to endometriosis-related chronic pain
Trial sites (1)
Facility
City
Region
Status
Pain Centre, Department of Anaesthesiology and Intensive Care Medicine Östra, Sahlgrenska University Hospital, Region Västra Götaland
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time.
