Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact
Clinical Trials in Sweden / NCT03720860
Recruiting Observational

Inflammatory Mediators of Acute Kidney Injury in Intensive Care

NCT03720860 · tracked via the Priya Life Science Sweden tracker
Sponsor
Uppsala University
Phase
Observational
Started
2018-01-01
Last updated
2026-01-12

Condition(s) studied

SepsisSurgeryAcute Kidney Injury

Study summary

Acute kidney injury (AKI) affects more than 50% of patients admitted to the intensive care unit. The most common underlying cause is sepsis. Severe AKI in combination with sepsis is associated with high mortality. The mechanisms for sepsis-induced AKI are largely unknown. Our hypothesis is that the inflammatory response to an infection cause collateral damage to host tissue and contributes to the development of AKI. In this study we want to investigate the presence of novel inflammatory mediators in patients with sepsis, patients subjected to major surgery (sterile inflammation) and non-inflamed patients and correlate their levels with the risk for AKI.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: Patients admitted to the intensive/post operative care unit * with septic shock or * post major surgery or * after intoxication with a chemical compund Exclusion Criteria: * Pregnancy or * Breast feeding or * Chronic kidney disease or * intoxication with nephrotoxic compund or * lack of informed consent

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Akademiska sjukhuset, Centraloperation Uppsala Uppsala County Recruiting

More Uppsala University trials in Sweden

Establishment of Reference Limits for Blood Lactate Levels in Intensive Care Patients With a Particular Focus on Age and Sex Active, not recruiting
Baby Swim As an Intervention for Depressive Symptoms and Lacking Attachment During the Postpartum Period Recruiting
Long-Term Opioid Therapy in Chronic Non-Cancer Pain: Risks and Benefits Enrolling by invitation
Treating Emergency Laparotomy Incisions With Negative Pressure Wound Therapy Recruiting
Patients With Long-stay at ICU: Factors and Evaluation - Feasibility Study Starting soon

Other trials for the same condition

Establishment of Reference Limits for Blood Lactate Levels in Intensive Care Patients With a Particular Focus on Age and Sex Active, not recruiting
Sepsis in the ICU-II Active, not recruiting
Timing of Renal Replacement Therapy in the Critically Ill Patients Recruiting
Bacteremia From Periodontal Treatment to Elucidate the Underpinnings of Sepsis Active, not recruiting
Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT03720860 on ClinicalTrials.gov ↗ ← All trials in Sweden