Combination vs. Monotherapy for Stenotrophomonas Maltophilia Infections

Inclusion Criteria: * Adult patients * S. maltophilia infections * Different episodes if a new infection ocurred \> 30 days since the index episode Exclusion Criteria: * isolates obtained from patients outside of hospital admission * microbiological or clinical colonization * hospitalizations shorter than 72 hours since the time zero * patients who died in the first 72 hours since the time zero or who were in imminent risk of death * polymicrobial infections * receipt of inappropriate therapy after the time of the emulated randomization, defined as the absence of in vitro active antimicrobials or the administration of active antimicrobials for less than 48 hours * absence of data outcomes