Ireland
--:--IST
Recruiting Not applicable

High-intensity Functional Training on Functional and Cognitive Performance in People with Parkinson's Disease.

NCT06879821 · tracked via the Priya Life Science Spain tracker
Sponsor
Fundacion Para La Investigacion Hospital La Fe
Phase
Not applicable
Started
2022-03-14
Last updated
2025-03-17

Condition(s) studied

Parkinson Disease

Investigational drug(s) / intervention(s)

high intensity functional training

high intensity functional training: The pillar of rehabilitation will be based on high intensity functional training. 45-minute sessions divided into 5 minutes of warm-up, 35 minutes of functional exercises, and 5 minutes of going back to bed and cooling down. The 35 minutes of exercises were divided into 3 categories: lower extremity exercises, upper extremity exercises, and static and dynamic coordination and balance exercises. Each category will consist of 3 exercises per session, performing 2-3 series with a maximum of repetitions of 10-RM. The progression of the load will be progressively increased in weeks 3, 5 and 8 between 40-60% of the 1-RM.

Study summary

Parkinson's disease (PD) is a progressive and chronic neurodegenerative disease, which presents signs and symptoms both motor (impaired gait, posture, balance, etc.) and cognitive (memory loss, dementia, etc.), all of which are causing disability and assuming a high economic cost. Currently, there are already certain authors who have shown how a high-intensity interval training (HIIT) protocol produces improvements in cognitive and physical performance in healthy adults6 and in people with multiple sclerosis. However, another modality has been created, such as high-intensity functional training (HIFT), which can benefit different populations, both healthy and pathological, due to the multimodal nature of the exercises. Thanks to multimodality, more aspects such as agility, coordination and precision of movements are worked on compared to unimodal HIIT programs that make this relevant work difficult in a person's daily life. The current study aims to demonstrate the effectiveness of a HIFT training protocol in a specific population, such as people with Parkinson's disease.

Eligibility

Sex
ALL
Min age
40 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: * Diagnosis of Parkinson's disease. * Stage I or II (Hoehn - Yahr Scale). * Age between 45 and 80 years. * Independent ambulation for 10 consecutive minutes. * Regular physical exercise. Exclusion Criteria: * Medical contraindication for physical activity, deafness or limited hearing and very low vision or blind. * Vestibular disorders that compromise balance. * Psychotic or severe cognitive disorder. * Decompensation or changes in medication. * Surgical intervention in the last 6 months. * Sedentary persons

Primary outcome measure(s)

  • Short physical performance battery (SSPB) — 10 minutes
    Functional performance evaluation.
  • Trail Making Test A y B — 15 minutes
    Evaluation of visual search, scanning, processing speed, mental flexibility and executive functions.

Trial sites (1)

FacilityCityRegionStatus
University of Valencia Valencia Valencia Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06879821 on ClinicalTrials.gov ↗ ← All trials in Spain