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Clinical Trials in Spain / NCT06690385
Recruiting Observational

DEPRECAP: Lung Cancer Screening Programme by LDCT for Patients With COPD or Emphysema.

NCT06690385 · tracked via the Priya Life Science Spain tracker
Sponsor
Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Phase
Observational
Started
2014-01-14
Last updated
2024-11-15

Condition(s) studied

Lung CancerCOPDEmphysema

Study summary

The DEPRECAP (Early detection of lung cancer) study is an ongoing, prospective, longitudinal, multicenter lung cancer screening program that recruited individuals with COPD or emphysema from the pulmonary clinics of Fundación Jiménez Díaz University Hospital and Villalba General Hospital, in Madrid, Spain.

The aim of this observational study is to determine the scientific evidence needed to study the benefit and potential effects of lung cancer screening in this group of patients and to determine the long-term effects of the intervention in reducing the high mortality rates associated with late-stage lung cancer diagnosis in a very high-risk population, to address under-diagnosis of COPD and to promote smoking cessation. This leads to the creation of a registry with clinical, radiological, functional data and biological samples for future studies in this cohort of patients to provide the scientific evidence needed to study the benefit and potential effects of screening for lung cancer and other tobacco-related pathologies diagnosed by Low-dose CT (LDCT)

Eligibility

Sex
ALL
Min age
55 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria: * Current or former smokers (\>15 years of abstinence) with a cumulative smoking exposure of \> 30 pack-years * Diagnosis of COPD according to the GOLD guidelines and/or emphysema identified by LDCT and/or a carbon monoxide diffusing capacity (DLCO) lower than 80% of predicted (as per the Global Lung Function Initiative (GLI) equations) Exclusion Criteria: * Individuals with a recent history of cancer (except non-melanoma skin cancer or carcinoma in situ) as well as those with other medical conditions that posed a significant risk of death were excluded from the study.

Primary outcome measure(s)

  • Lung cancer screening — 15 years
    Creation of a multi-centre pilot lung cancer screening programme targeting high-risk subjects. with COPD and emphysema.

Trial sites (2)

FacilityCityRegionStatus
Fundación Jimenez Díaz Universitary Hospital Madrid Spain Recruiting
Pneumology department. Fundación Jimenez Díaz University Hospital Madrid Spain Recruiting

More Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz trials in Spain

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06690385 on ClinicalTrials.gov ↗ ← All trials in Spain