Coronary Rotational Atherectomy Elective vs. Bailout in Severely Calcified Lesions and Chronic Renal Failure

Condition(s) studied

Investigational drug(s) / intervention(s)

Percutaneous coronary intervention (PCI): Optimal stent expansion by IVUS-guided PCI.

Study summary

The current role of the rotational atherectomy is for non-dilatable coronary lesions and for severely calcified lesions that may interfere with optimal stent expansion.

Severely calcified coronary lesions are associated with worse outcomes. In this regard, chronic kidney disease is associated with severely calcified coronary arteries.

Some evidence suggests that elective rotational atherectomy used by experienced operators can be safe and effective, minimizing time and complications for patients with heavily calcified lesions.

However, there is no direct randomized comparison between rotational atherectomy and angioplasty alone in the setting of chronic renal failure and with intravascular ultrasound assessment for detecting severely calcified coronary arteries.

Eligibility

Primary outcome measure(s)

• The healthcare cost analysis between elective atherectomy and conventional atherectomy (bailout) — Periprocedural and 30 days after the procedure
  The costs included the items, supplies, and time used in the catheterization laboratory, and expenses caused by complications during hospital length of stay and 30 days after the procedure.

Trial sites (1)

Other trials for the same condition