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Clinical Trials in South Korea / NCT07691242
Starting soon Phase 1

Multiple Ascending Dose Study of DW4421

NCT07691242 · tracked via the Priya Life Science South Korea tracker
Sponsor
Daewon Pharmaceutical Co., Ltd
Phase
Phase 1
Started
2026-09
Last updated
2026-07-08

Condition(s) studied

Healthy Adult Volunteers

Investigational drug(s) / intervention(s)

DW4421S-T0DW4421S-T2DW4421S-T1 →DW4421S-T3DW4421S →DW4421-3

DW4421S-T0: DW4421 5mg

DW4421S-T2: DW4421 15mg

DW4421S-T1: DW4421 20mg

DW4421S-T3: DW4421 30mg

DW4421S: DW4421 40mg

DW4421-3: Zastaprazan 20mg

Study summary

Multiple Ascending Dose of DW4421, phase I

Eligibility

Sex
ALL
Min age
19 Years
Max age
50 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Healthy adult aged 19 to 50 (inclusive) years, at the time of screening. * Subjects weighing between 50 kg and 90 kg with BMI between 18 and 27 kg/m2 (inclusive) at screening visit. Exclusion Criteria: * Those who have clinical significant liver, kidney, nervous system, respiratory, endocrine, hematology and oncology, cardiovascular, urinary, and mental diseases or past history.

Primary outcome measure(s)

  • AUCτ,ss, Area under the drug concentration-time curve of DW4421 following multiple oral administration — Day 7
    Assessment of pharmacokinetic parameters of DW4421 after multiple oral administration
  • Cmax of DW4421 following multiple oral administration — Day 7
    Assessment of pharmacokinetic parameters of DW4421 after multiple oral administration

Trial sites (1)

FacilityCityRegionStatus
Chungbuk National University Hospital Cheongju-si North Chungcheong

More Daewon Pharmaceutical Co., Ltd. trials in South Korea

Evaluate the Safety, Tolerability and Pharmacokinetics of DW5524 in Healthy Adult Volunteers Starting soon
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetics of DW4421-T1 and DW4421S-T1 in Healthy Adult Volunteers Starting soon
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetics of DW4421 and DW4421S in Healthy Adult Volunteers Enrolling by invitation
Study to Evaluate the Efficacy and Safety of DW1807 in Perennial Allergic Rhinitis Patients With Asthma Recruiting
A Phase 1 Clinical Trial to Evaluate the Safety and DDI of DW4421 and 3 NSAIDs Recruiting

Other trials for the same condition

Drug-Drug Interaction Between DW4421 and Amoxicillin/Clarithromycin Starting soon
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07691242 on ClinicalTrials.gov ↗ ← All trials in South Korea