ISB With SSNB & ANB

Condition(s) studied

Investigational drug(s) / intervention(s)

Preemptive ultrasound-guided interscalene brachial plexus block and suprascapular nerve block and axillary nerve block: Preemptive ultrasound-guided interscalene brachial plexus block using ropivacaine, and suprascapular nerve block and axillary nerve block using ropivacaine or saline. Low fixed dose patient controlled analgesia (PCA) were done in the two group.

Study summary

This study is a prospective, randomized, double-blind trial comparing patients who underwent arthroscopic rotator cuff repair and received an interscalene brachial plexus block (9 ml of 0.75% ropivacaine, 3 ml for each trunk) combined with suprascapular nerve block and axillary nerve block (each with 10 ml of 0.75% ropivacaine) versus those who received an interscalene brachial plexus block (9 ml of 0.75% ropivacaine, 3 ml for each trunk) combined with placebo suprascapular and axillary nerve blocks (each with 10 ml of 0.9% saline).

The study will compare subjective pain scores (VAS score) and patient satisfaction preoperatively and at 1, 3, 6, 12, 18, 24, 36, and 48 hours postoperatively. Additionally, 5 ml of venous blood will be collected preoperatively and at 1, 6, 12, 24, and 48 hours postoperatively to analyze and compare serum levels of cortisol, IL-6, IL-8, IL-1β, substance P, serotonin, β-endorphin, and norepinephrine.

Eligibility

Primary outcome measure(s)

• visual analog pain scale (VAS) — preoperative, postoperative 1, 3, 6, 12, 18, 24, 36, 48 hour(s)
  0-10, 0: no pain, 10: very severe pain

Trial sites (2)

More Chuncheon Sacred Heart Hospital trials in South Korea

Other trials for the same condition