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Recruiting Observational

Double Unit Cord Blood Transplant in Hematologic Malignancies.

NCT06712108 · tracked via the Priya Life Science South Korea tracker
Phase
Observational
Started
2023-12-21
Last updated
2026-02-02

Condition(s) studied

Adult Double Unit Cord Blood Transplant

Investigational drug(s) / intervention(s)

tranplant

tranplant: double unit cord blood transplnat

Study summary

The efficacy and safety of non-myeloablative and myeloablative preconditioning followed by dual-unit umbilical cord blood transplantation from unrelated donors in adult patients with malignant hematologic diseases eligible for allogeneic hematopoietic stem cell transplantation are evaluated through prospective observation and analysis of actual clinical data collection

Eligibility

Sex
ALL
Min age
19 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Aged 19 and older * Patients scheduled for umbilical cord blood transplantation as a primary allogeneic hematopoietic stem cell transplantation for the treatment of the following hematologic diseases: Acute leukemia (myeloid/lymphoid/mixed lineage) / Myelodysplastic syndromes / Chronic leukemia (myeloid/lymphoid/monocytic) and myeloproliferative neoplasms / Malignant lymphomas, multiple myeloma / Other malignant hematologic malignancies / bone marrow failure diseases, including aplastic anemia \- If all contents of the consent form are understood and consented to in writing. Exclusion Criteria: * Patients with a history of allogeneic hematopoietic stem cell transplantation or those undergoing transplantation for the treatment of engraftment failure (secondary allogeneic hematopoietic stem cell transplantation is an exclusion criterion; however, patients eligible for registration include those undergoing their first allogeneic stem cell transplantation following an autologous stem cell transplantation). * Patients with severe, uncontrolled infections or severe cardiopulmonary dysfunction, as judged by the investigator. * Patients with an ECOG Performance Status (PS) greater than 3 or those receiving mechanical ventilation in the intensive care unit. * Patients who do not consent to participate in the study or those deemed unsuitable for sincere participation by the attending physician.

Primary outcome measure(s)

  • Overall Survival — 2 years

Trial sites (6)

FacilityCityRegionStatus
Jeonbuk National University Hopital Jeonju Jeonlabuk-do Not Yet Recruiting
Keimyung Unversity Dongsan Hospital Daegu South Korea Not Yet Recruiting
Dong-A University Hospital Pusan South Korea Not Yet Recruiting
Pusan National University Hospital Pusan South Korea Not Yet Recruiting
Seoul National University Bundang Hospital Seongnam South Korea Not Yet Recruiting
Seoul National University Hospital Seoul South Korea Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06712108 on ClinicalTrials.gov ↗ ← All trials in South Korea