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Recruiting Observational

Comparison of Functional Recovery After Total Knee Arthroplasty Between Low Phase Angle and High Phase Angle Group

NCT06701474 · tracked via the Priya Life Science South Korea tracker
Phase
Observational
Started
2024-09-13
Last updated
2025-02-07

Condition(s) studied

Knee Osteoarthritis

Study summary

The goal of this observational study is to compare the functional outcome of patients with end-stage knee osteoarthritis (OA) before and after total knee arthroplasty based on the phase angle level.

The main questions it aims to answer are:

* Do patients with low phase angle show worse functional recovery after total knee arthroplasty compared to those with high phase angle?
* Is postoperative physical function associated with preoperative phase angle level?

Researchers will compare postoperative physical function and muscle strength between the low and high phase angle groups to determine whether a low phase angle is associated with poorer functional recovery.

Participants will:

Perform physical function tests, isokinetic strength assessments, and bioelectrical impedance analysis before and three months after surgery.

Eligibility

Sex
ALL
Min age
55 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Individuals aged 55 and over (based on the age on their national ID at the time of consent) * Individuals diagnosed with knee OA based on medical history, physical examination, and radiographic assessments. * Individuals who plan to perform total knee arthroplasty Exclusion Criteria: * Individuals with gait disturbance due to neurologic disorders such as Parkinson disease, stroke and dementia * Individuals with severe cardiac, pulmonary, or musculoskeletal disorders that limited quadriceps strength and physical function * Individuals with knee osteoarthritis due to secondary causes such as rheumatic or traumatic arthritis * Individuals with a history of any knee surgery within one year. * Individuals considered clinically unsuitable for the study by the researchers or person in charge based on significant medical findings.

Primary outcome measure(s)

  • Timed up and go test (TUG) — Baseline and 3 months after surgery
    Researchers ask patients to rise from a seated position, walk a distance of 3 m, turn around, return to the chair, and sit back. The average time of three trials was recorded as a result
  • 10 meter walk test (10MWT) — Baseline and 3 months after surgery
    Patients are instructed to walk 14 m, including 2 m at both ends for acceleration and deceleration, at their comfortable speed. Gait speed was calculated by dividing the 10m distance by the time taken.
  • Berg balance scale (BBS) — Baseline and 3 months after surgery
    Patients are asked to perform 14 tasks regarding the static and dynamic balance of patients. Each task was rated on a five-point scale from 0 to 4, with a total score of 56.

Trial sites (1)

FacilityCityRegionStatus
Yongin Severance Hospital Yongin-si Gyeonggi-do Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06701474 on ClinicalTrials.gov ↗ ← All trials in South Korea