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Clinical Trials in South Korea / NCT06168292
Recruiting Not applicable

Intraductal Radiofrequency Thermoablation and Radiotherapy Combined Treatment for Extrahepatic Cholangiocarcinoma

NCT06168292 · tracked via the Priya Life Science South Korea tracker
Sponsor
National Cancer Center, Korea
Phase
Not applicable
Started
2024-04-01
Last updated
2025-06-19

Condition(s) studied

Biliary Tract CarcinomaRadiotherapyRadio-frequency Ablation

Investigational drug(s) / intervention(s)

ID-RFA and Radiotherapy

ID-RFA and Radiotherapy: The histologic or cytologic examination will be performed at the time of the first biliary drainage, and the extent of the cholangiocarcinoma lesion will be assessed during the procedure. After the diagnosis of extrahepatic cholangiocarcinoma, ID-RFA will be performed, and a biliary stent will be inserted for biliary drainage. Radiotherapy will be performed within 1 month of ID-RFA.

Study summary

\[Study objectives\] To evaluate the efficacy and safety of the combined treatment of radiotherapy and endoscopic intraductal radiofrequency ablation in patients with locoregional extrahepatic cholangiocarcinoma.

Eligibility

Sex
ALL
Min age
20 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: 1. Patients 20 years of age or older, who voluntarily agree to participate in the study and sign the informed consent. 2. Patients with cytopathologically diagnosed inoperable extrahepatic cholangiocarcinoma Exclusion Criteria: 1. Patients who refuse to sign the informed consent 2. Patients with metastatic cancer (stage IV) or malignant ascites 3. Patients with intrahepatic cholangiocarcinoma 4. Patients who are unable to undergo endoscopic procedures as determined by the investigator. 5. Patients with a life expectancy of 3 months or less 6. Patients with ID-RFA contraindications: pacemaker, pregnancy, uncorrected bleeding tendency (PT INR \> 1.5, platelets \< 50,000/mm3)

Primary outcome measure(s)

  • 2-year local control rate — At 2 years from the date of study enrollment
    2-year local control rate

Trial sites (1)

FacilityCityRegionStatus
National Cancer Center, Korea Goyang-si Other Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06168292 on ClinicalTrials.gov ↗ ← All trials in South Korea