A Study of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas (Scalp, Genital, and/or Palms of the Hands and the Soles of the Feet)
Condition(s) studied
Investigational drug(s) / intervention(s)
JNJ-77242113: JNJ-77242113 will be administered orally.
Placebo: Placebo will be administered orally.
Study summary
The purpose of the study is to see how effective JNJ-77242113 is in participants with plaque psoriasis affecting special areas (scalp, genital, and/or palms of the hands and the soles of the feet).
Eligibility
Primary outcome measure(s)
- Percentage of Participants Who Achieved an Investigator's Global Assessment (IGA) Score of 0 or 1 and a Greater Than or Equal to (>=) 2-Grade Improvement From Baseline at Week 16 — Week 16
IGA assesses participant's plaque psoriasis. Lesions were graded for induration, erythema, scaling, each using 5 point scale. Induration:0=no evidence of plaque elevation, 1=minimal plaque elevation,=0.25 millimeters(mm); 2=mild plaque elevation,=0.5 mm; 3=moderate plaque elevation,=0.75 mm; 4=severe plaque elevation,\>1 mm; Erythema: 0=no evidence of erythema, hyperpigmentation may be present, 1=faint erythema, 2=light red coloration, 3=moderate red coloration, 4=bright red coloration; Scaling: 0=no evidence of scaling, 1=minimal; occasional fine scale over less than 5% of lesion, 2=mild; fine scale dominates, 3=moderate; coarse scale predominates, 4=severe; thick, scale predominates. Final IGA score was based upon average of induration, erythema and scaling scores assessed on 5 point scale: cleared (0), minimal (1), mild (2), moderate (3), or severe(4). Higher score=more severe disease. Baseline=closest measurement taken prior to or at time of first study drug administration date.
Trial sites (90)
| Facility | City | Region | Status |
|---|---|---|---|
| Center for Dermatology and Plastic Surgery | Scottsdale | Arizona | |
| Johnson Dermatology | Fort Smith | Arkansas | |
| California Dermatology & Clinical Research Institute | Encinitas | California | |
| Forcare Clinical Research Inc | Tampa | Florida | |
| Hamilton Research LLC | Alpharetta | Georgia | |
| Arlington Dermatology | Rolling Meadows | Illinois | |
| Dundee Dermatology | West Dundee | Illinois | |
| Dawes Fretzin Clinical Research Group LLC | Indianapolis | Indiana | |
| Indiana Clinical Trial Center | Plainfield | Indiana | |
| Dermatology and Advanced Aesthetics | Lake Charles | Louisiana | |
| Allcutis Research 1 | Beverly | Massachusetts | |
| Hamzavi Dermatology | Fort Gratiot | Michigan | |
| Minnesota Clinical Study Center | New Brighton | Minnesota | |
| MediSearch Clinical Trials | Saint Joseph | Missouri | |
| Skin Specialists | Omaha | Nebraska | |
| Schweiger Dermatology Group | East Windsor | New Jersey | |
| Optima Research | Boardman | Ohio | |
| Oregon Dermatology and Research Center | Portland | Oregon | |
| Paddington Testing Co, Inc. | Philadelphia | Pennsylvania | |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | |
| Arlington Research Center, Inc. | Arlington | Texas | |
| Center for Clinical Studies 1 | Houston | Texas | |
| Austin Institute for Clinical Research | Pflugerville | Texas | |
| Progressive Clinical Research | San Antonio | Texas | |
| Dermatology Clinical Research Center of San Antonio | San Antonio | Texas | |
| Center for Clinical Studies | Webster | Texas | |
| Cope Family Medicine - Ogden Clinic | Bountiful | Utah | |
| Frontier Derm Partners CRO, LLC | Mill Creek | Washington | |
| CIPREC | Buenos Aires | Argentina | |
| Centro Privado de Medicina Familiar | Buenos Aires | Argentina | |
| Conexa Investigacion Clinica S.A. | CABA | Argentina | |
| CEDIC Centro de Investigacion clinica | Caba | Argentina | |
| Alberta DermaSurgery Centre | Edmonton | Alberta | |
| Lynderm Research Inc. | Markham | Ontario | |
| Skin Centre for Dermatology | Peterborough | Ontario | |
| York Dermatology Clinic and Research Centre | Richmond Hill | Ontario | |
| Innovaderm Research Inc. | Montreal | Quebec | |
| Centre Dermatologique | Québec | Quebec | |
| Skinsense Medical Research | Saskatoon | Saskatchewan | |
| ISA - Interdisciplinary Study Association GmbH | Berlin | Germany |
+ 50 more sites — see the full list on the official registry below.
More Janssen Research & Development, LLC trials in South Korea
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06095102 on ClinicalTrials.gov ↗ ← All trials in South Korea