Effects of Pitavastatin or Combination of Pitavastatin and Ezetimibe on Glucose Metabolism Compared to AtoRvastatin in atheroscLerotic Cardiovascular Disease Patients With Metabolic Syndrome: The EZ-PEARL Randomized Trial
Condition(s) studied
Investigational drug(s) / intervention(s)
Pitavastatin: Pitavastatin 4 mg will be given.
Pitavastatin plus Ezetemibe: Pitvastatin 4 mg plus ezetemibe 10 mg will be given.
Atorvastatin: Atorvastatin 40 mg will be given.
Study summary
The purpose of this study was to investigate the effect of pitavastatin or pitavastatin and ezetimibe combination therapy on glucose metabolism compared to atorvastatin in patients with atherosclerotic cardiovascular disease with metabolic syndrome.
Eligibility
Primary outcome measure(s)
- Change form baseline homeostatic model assessment for insulin resistance (HOMA-IR) at 24 weeks — At 24 weeks
Changes of homeostatic model assessment for insulin resistance (HOMA-IR) form baseline to 24 weeks will be compared among the three groups.
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Yonsei University Health System, Severance Hospital | Seoul | South Korea | Recruiting |
On this site
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Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT05705804 on ClinicalTrials.gov ↗ ← All trials in South Korea