Long-term Anticoagulation With Oral Factor Xa Inhibitor Versus Vitamin K Antagonist After Mechanical Aortic Valve Replacement

Inclusion Criteria: 1. Age 19 and more 2. At least 3 months after mechanical aortic valve replacement 3. At least one of the conditions(as defined below) is met * The New York Heart Association (NYHA) Functional Classification I or II; or * According to the Valve Academic Research Consortium(VARC)2 criteria, confirmed proper valve function: no prosthesis-patient mismatch and mean aortic valve gradient \<20 mm Hg or peak velocity \<3 m/s, AND no moderate or severe prosthetic valve regurgitation 4. Voluntarily participated in the written agreement Exclusion Criteria: 1. Old-generation mechanical valve 2. History of mechanical valve implantation in the mitral valve, pulmonary valve, or tricuspid valve 3. Valvular atrial fibrillation(atrial fibrillation with moderate or severe mitral stenosis) 4. Moderate to severe mitral stenosis or regurgitation 5. History of hemorrhagic stroke 6. Clinically overt stroke within the last 3 months 7. Renal failure(creatinine clearance \<15mL/min) or on hemodialysis 8. Left ventricular dysfunction: Left ventricular ejection fraction (LVEF) ≤40% 9. Child-Pugh B and C hepatic impairment or any hepatic disease associated with coagulopathy 10. Clinically significant active bleeding 11. Bleeding or hemorrhagic disorder 12. The increased risk of bleeding due to the following reasons 1. History of gastrointestinal ulcers or active ulcerations within the last 6 months 2. History of intracranial or intracerebral hemorrhage within the last 6 months 3. Spinal cord vascular abnormalities or intracerebral vascular abnormalities 4. History of the brain, spinal cord, or ophthalmic surgery within the last 6 months 5. History of the brain or spinal cord injury within the last 6 months 6. History of the brain or spinal cord injury or spinal tap, major regional anesthesia, or spinal anesthesia within the last 6 months 7. Esophageal varices 8. Arteriovenous malformation 9. Vascular aneurysms 10. Malignant tumor with a high risk of bleeding 13. Bleeding tendencies associated with overt bleeding of 1. gastrointestinal, genitourinary, respiratory tract, or colorectal cancer 2. cerebrovascular hemorrhage 3. aneurysms- cerebral, dissecting aorta 4. pericarditis and pericardial effusions 5. bacterial endocarditis 14. Hemodynamically unstable or pulmonary embolism required thrombolysis or embolectomy 15. Combination therapy with other anticoagulants(Unfractionated heparin(UFH), enoxaparin, dalteparin, fondaparinux, etc.) However, the following cases are permitted * Switching anticoagulants * Intravenous UFH to keep central/arterial lines open 16. Uncontrolled moderate or severe hypertension 17. Anemia at least one among the conditions(as defined below) is met 1) Hemoglobin level \<10.0 g/dL or platelet count \< 100 x 10x9/L within the last 6 months 2) Diagnosed and documented ongoing anemia 18. Infective endocarditis 19. Hypersensitivity to the main component or constituents of Rivaroxaban or Vitamin K antagonist 20. Positive pregnancy test results (all pregnant women should undergo urinary human chorionic gonadotropin (hCG) testing within 7 days before screening and/or randomization) or during pregnancy or lactation 21. A genetic problem with galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption 22. The unsuitable condition of the protocol 23. Actively participating in another drug or device investigational study, which has not completed the primary endpoint follow-up period 24. Terminal illness with life expectancy \<12 months 25. Vitamin K deficiency 26. Alcoholic or psychical disorder 27. Threatened abortion, eclampsia, or preeclampsia 28. Concomitant use with antiplatelet in patients with a history of stroke or transient ischemic attack for the treatment of the acute coronary syndrome