Molecular Profiling in Young (<50 Years of Age) Patients With Metastatic Breast Cancer

Condition(s) studied

Investigational drug(s) / intervention(s)

FoundationOne CDx: FoundationOne CDx will be performed using archival tumor tissue

Study summary

Breast cancer is the most common cancer in women worldwide, especially in developed countries. In developing countries, including South Korea, the incidence and mortality rate of breast cancer is rapidly increasing. One of the most important characteristics of breast cancer in South Korea, as well as in other Asian countries, is the younger onset of disease compared to Western.

Medical treatment of breast cancer is evolving rapidly, incorporating immune checkpoint blockades and molecularly targeted agents. However, data and knowledge are still limited in terms of molecular characteristics of Asian breast cancer, compared to that of Western countries, and this remains a major hurdle for drug development in Asian breast cancer patients.

The primary objective of this study is to elucidate the genetic characteristic of young (\<50 years of age) Korean patients with metastatic breast cancer using FoundationOne CDx.

Eligibility

Primary outcome measure(s)

• Genetic characteristic of young (<50 years of age) Korean patients with metastatic breast cancer. — After the end of patient enrollment
  Genetic characteristics will be evaluated using FoundationOne CDx.

Trial sites (1)

More Seoul National University Hospital trials in South Korea

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