Clinical Trials in South Korea / NCT02208388
Recruiting
Not applicable
Prospective Evaluation of MyocaRdial PerFUSion ComputEd Tomography Trial
NCT02208388 · tracked via the Priya Life Science South Korea tracker
Condition(s) studied
Coronary Disease
Investigational drug(s) / intervention(s)
computed tomography perfusion guided treatmentFractional flow reserve guided treatment
Study summary
The purpose of this study is to evaluate safety and effectiveness of CTP(computed tomography perfusion) guided revascularization vs FFR(Fractional flow reserve) guided revascularization
Eligibility
Inclusion Criteria:
* Age 20 and more
* Diagnosed angina or angina equivalent symptom or positive exercise treadmill test
* Patients with intermediate- or high-risk probability of CAD defined by Diamond and Forester
* 70 % stenosis or more in coronary CTA
* Willing to provide informed, written consent
Exclusion Criteria:
* Requirement for surgical procedure
* Cardiogenic shock and/or need for mechanical/pharmacologic hemodynamic support
* Recent STEMI (\<5 days)
* Non STEMI, if the cardiac troponin is not stable or starting to decline
* Left ventricular ejection fraction \<30%
* Life expectancy \<2 years
* Impaired renal function with an effective glomerular filtration rate less than 30mL/min/1.73 ㎡ or creatinine more than 2.0 mg/dL
* Undergoing evaluation for organ transplantation
* Participation or planned participation in another cardiovascular clinical trial
* Pregnancy
* Inability to take dual antiplatelet therapy for six months
* Previous CABG
* Left main disease requiring revascularization
* Any target lesion with in-stent restenosis
* NYHA class 3 or 4a
* Severe and persistent angina with severe limitation in everyday living activities (Canadian Cardiovascular Society grading Class IV)
Primary outcome measure(s)
- Composite Events — 1 year
All cause death, Myocardial infarction, Diseased-related unplanned hospitalization or stroke
Trial sites (7)
| Facility | City | Region | Status |
|---|---|---|---|
| Asan Medical Center | Seoul | Songpa-Gu | Recruiting |
| Hallym University Sacred Heart Hospital | Anyang | South Korea | Completed |
| Gangwon National Univ. Hospital | Chuncheon | South Korea | Completed |
| Keimyung University Dongsan Medical Center | Daegu | South Korea | Completed |
| Pusan National University Hospital | Pusan | South Korea | Enrolling By Invitation |
| Pusan National University Yangsan Hospital | Pusan | South Korea | Completed |
| Severance Hospital | Seoul | South Korea | Withdrawn |
Other trials for the same condition
Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT02208388 on ClinicalTrials.gov ↗ ← All trials in South Korea