A Study of Tirzepatide (LY3298176) Once Weekly in Adolescent Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
Condition(s) studied
Investigational drug(s) / intervention(s)
Tirzepatide: Administered SC
Placebo: Administered SC
Study summary
The main purpose of this study is to evaluate the safety and efficacy of tirzepatide in adolescents that have obesity or overweight with at least one weight-related comorbidity. The study will last approximately 90 weeks and may include up to 25 visits.
Participants who have completed the primary 72-week GPHP study and have been off treatment for no more than 12 weeks (including the 4-week safety follow-up period), will have the opportunity to receive an additional 156 weeks of treatment with tirzepatide as well as continuing the lifestyle intervention.
Eligibility
Primary outcome measure(s)
- Percent Change from Baseline in Body Mass Index (BMI) — Baseline, Week 72
Trial sites (33)
| Facility | City | Region | Status |
|---|---|---|---|
| CenExel iResearch, LLC | Decatur | Georgia | |
| Solaris Clinical Research | Meridian | Idaho | |
| Cotton O'Neil Diabetes & Endocrinology | Topeka | Kansas | |
| Pennington Biomedical Research Center | Baton Rouge | Louisiana | |
| Barry J. Reiner, MD, LLC | Baltimore | Maryland | |
| M Health Fairview - Delaware Clinical Research Unit (DCRU) | Minneapolis | Minnesota | |
| Washington University School of Medicine | St Louis | Missouri | |
| Aventiv Research Inc | Columbus | Ohio | |
| PriMED Clinical Research | Dayton | Ohio | |
| Vanderbilt Health One Hundred Oaks | Nashville | Tennessee | |
| Alberta Diabetes Institute | Edmonton | Alberta | |
| The Wharton Medical Clinic Clinical Trials Inc | Hamilton | Ontario | |
| The Hospital for Sick Children | Toronto | Ontario | |
| CIUSSS- saguenay-Lac-Saint-Jean | Chicoutimi | Quebec | |
| ReFit Clinic | Olomouc | Olomouc Region | |
| Nemocnice AGEL Ostrava - Vitkovice a.s. | Ostrava | Ostrava Město | |
| Fakultni nemocnice v Motole | Prague | Praha 5 | |
| Nemocnice Jihlava | Jihlava | Czechia | |
| Fakultni nemocnice Kralovske Vinohrady | Prague | Czechia | |
| Yitzhak Shamir Medical Center | Beer Yaacov | Central District | |
| Schneider Children's Medical Center | Petah Tikva | Central District | |
| Sheba Medical Center | Ramat Gan | Central District | |
| Shaare Zedek Medical Center | Jerusalem | Jerusalem | |
| Emek Medical Center | Afula | Northern District | |
| Rambam Health Care Campus | Haifa | Northern District | |
| Soroka Medical Center | Beersheba | Southern District | |
| IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola | Bologna | Emilia-Romagna | |
| Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Trento | Verona | Veneto | |
| Azienda Ospedaliera Universitaria Di Messina G. Martino | Messina | Italy | |
| Azienda Ospedaliero Universitaria Maggiore della Carità | Novara | Italy | |
| Instytut Diabetologii | Warsaw | Masovian Voivodeship | |
| Samodzielny Publiczny Szpital Kliniczny nr 1 SUM | Zabrze | Silesian Voivodeship | |
| Centralny Szpital Kliniczny Uniwersytetu Medycznego w Lodzi, Uniwersyteckie Centrum Pediatrii im. M. Konop -T | Lodz | Łódź Voivodeship |
On this site
📄 Mounjaro (tirzepatide) drug profile →More Eli Lilly and Company trials in Poland
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06075667 on ClinicalTrials.gov ↗ ← All trials in Poland