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Trackers› Clinical trials› Netherlands
Clinical trial register · Netherlands

Studies with a Dutch investigative site

Every study on the ClinicalTrials.gov registry that lists a site in Netherlands and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 3203 matching records held by the registry are in this view. Synced 26 Sep 2026, 19:48 UTC
3203
Studies in scope
all four open statuses
1832
Recruiting now
open to new participants
608
Lead sponsors
across recruiting studies
Top sites
Amsterdam 1240 Rotterdam 867 Groningen 601 Nijmegen 559 Utrecht 541
Narrow the register
Recruitment status
Phase
Lead sponsor
Erasmus Medical Center162 Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)143 University Medical Center Groningen135 Radboud University Medical Center112 Maastricht University Medical Center87
Site location
Amsterdam1240 Rotterdam867 Groningen601 Nijmegen559 Utrecht541
All 161 locations
Target enrolment
to

Trials in this register

3203 of 3203 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Netherlands
Start
Active, closed
DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)
NCT05566795Low-grade Glioma, Rapidly Accelerated Fibrosarcoma (RAF) Altered Glioma, Pediatric Low-grade Glioma
DrugTovorafenib
Day One Biopharmaceuticals, Inc.
Phase 3
418
Utrecht
2023-02-27
Recruiting
Clinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders
NCT05656469Mood Disorders, Anxiety Disorders, Psychotic Disorders
Parnassia Groep
Not applicable
2,500
Amsterdam, Maastricht
2023-02-23
Recruiting
Iodine Uptake After a Low Iodine Diet
NCT05599139Differentiated Thyroid Cancer
University Medical Center Groningen
Not applicable
25
Groningen
2023-02-22
Active, closed
The UPDATE Trial (Uvb Phototherapy in Dermatology for ATopic Eczema)
NCT05704205Atopic Dermatitis Eczema, Atopic Dermatitis
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Not applicable
316
Almere Stad, 's-Hertogenbosch, Alkmaar, Amsterdam, Haarlem, Hoofddorp, Purmerend, Zwolle
2023-02-22
Recruiting
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
NCT05503797Cancer Harboring BRAF Alterations, HGG, LGG, Solid Tumors
Fore Biotherapeutics
Phase 2
254
Rotterdam
2023-02-21
Active, closed
Safety and Efficacy Study of Viaskin Peanut in Peanut-allergic Children 4-7 Years of Age
NCT05741476Allergy, Peanut
DBV Technologies
Phase 3
600
Rotterdam, Utrecht
2023-02-21
Recruiting
The (Cost-)Effectiveness of Surgical Excision of Colorectal Endometriosis Compared to ART Treatment Trajectory
NCT05677269Endometriosis, Rectum, Endometriosis of Colon, Subfertility, Female
Leiden University Medical Center
Observational
339
Eindhoven, Enschede, Groningen, Leiden, Maastricht, Nijmegen, Rotterdam, The Hague
2023-02-17
Recruiting
Selective Fetal Growth Restriction in Monochorionic Twins - an International Investigation
NCT05952583Twin; Pregnancy, Affecting Fetus or Newborn, Fetal Growth Retardation, Twin Monochorionic Diamniotic Placenta, Twin Diseases
Leiden University Medical Center
Observational
274
Leiden
2023-02-17
Recruiting
High-Risk prostatE Cancer radiatiOn Versus surgERy
NCT05931419Prostate Cancer, Prostate Adenocarcinoma
Comprehensive Cancer Centre The Netherlands
Observational
837
Alkmaar, Amsterdam, Assen, Beverwijk, Dordrecht, Eindhoven, Goes, Groningen
2023-02-16
Active, closed
the PHENOSAR Trial: Use of Antibiotics in Treatment of Sarcoidosis
NCT05291468Sarcoidosis, Pulmonary, Sarcoidosis Skin
St. Antonius Hospital
Not applicable
40
Nieuwegein
2023-02-15
Active, closed
A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE
NCT05702034Ischemic Stroke; Ischemic Attack, Transient
DrugMilvexian
Janssen Research & Development, LLC
Phase 3
12,523
Breda, Delft, Uden
2023-02-15
Recruiting
A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD
NCT05822908Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 3, Huntington Disease
Vico Therapeutics B. V.
Phase 1/2
68
Leiden, Nijmegen
2023-02-14
Recruiting
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
NCT05667142Primary Generalized Tonic-Clonic Seizures
DrugAzetukalner
Xenon Pharmaceuticals Inc.
Phase 3
160
Heeze
2023-02-14
Active, closed
Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD
NCT05711940Treatment Resistant Depression
DrugPsilocybin
COMPASS Pathways
Phase 3
572
Groningen, Leiden, Utrecht
2023-02-14
Active, closed
A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A
NCT05685238Haemophilia A, Haemophilia A With Inhibitors
Novo Nordisk A/S
Phase 3
451
Amsterdam, Utrecht
2023-02-13
Recruiting
Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies
NCT05682378Heterozygous or Homozygous Familial Hypercholesterolemia
DrugInclisiran
Novartis Pharmaceuticals
Phase 3
195
Amsterdam, Rotterdam
2023-02-10
Active, closed
Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma
NCT05605899High-risk Large B-cell Lymphoma (LBCL)
DrugsAxi-cel·Axicabtagene Ciloleucel·Vincristine·Doxorubicin
Kite, A Gilead Company
Phase 3
300
Amsterdam, Groningen, Leiden, Maastricht, Utrecht
2023-02-10
Recruiting
Subcutaneous Interval Lengthening of Vedolizumab for Economic Research
NCT06584162Inflammatory Bowel Diseases
DrugVedolizumab
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Phase 4
40
Amsterdam
2023-02-09
Active, closed
Rituximab Effect on Decreasing glUcoCorticoid Exposition in PolyMyalgia Rheumatica Patients Experiencing a PMR Relapse
NCT05533164Polymyalgia Rheumatica
DrugsRuxience·Truxima·Rituximab
Sint Maartenskliniek
Phase 3
174
Ubbergen
2023-02-09
Recruiting
Prospective Analysis of the Treatment of Progressive Familial Intrahepatic Cholestasis (TreatFIC)
NCT06778174Progressive Familial Intrahepatic Cholestasis
University Medical Center Groningen
Observational
200
Groningen
2023-02-09
Active, closed
A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)
NCT05578976Diffuse Large B-Cell Lymphoma
DrugsEpcoritamab·Vincristine·Doxorubicin·Prednisone
Genmab
Phase 3
900
Almere Stad, Apeldoorn, Nijmegen, Maastricht, Breda, Eindhoven, Tilburg, Alkmaar
2023-02-08
Recruiting
Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial
NCT05496998Mitral Regurgitation
Medtronic Cardiovascular
Not applicable
400
Eindhoven, Nieuwegein, Rotterdam
2023-02-07
Recruiting
A Study of ImmunoPet Imaging Using 89Zr-DFO-REGN5054 in Adult Participants With Solid Cancers Treated With Cemiplimab
NCT05259709Advanced Solid Tumor, Metastatic Solid Tumor
DrugCemiplimab
Regeneron Pharmaceuticals
Phase 1
50
Groningen
2023-02-07
Recruiting
Observational Dutch Young Symptomatic StrokE studY - nEXT
NCT05853796Ischemic Stroke, Stroke in the Young, Cardiovascular Diseases, Cerebrovascular Disorders
Radboud University Medical Center
Observational
280
Nijmegen, Eindhoven, Enschede, Zwolle, The Hague, Leeuwarden
2023-02-06
Active, closed
Quality of Life After Hyperbaric Oxygen Therapy in Post-COVID Patients
NCT06159309Long COVID, Long COVID-19 Syndrome, Long Covid19, Long Covid 19
Rutger Lalieu
Observational
200
Hoogeveen, Geldrop, Waalwijk, Rijswijk, Rotterdam, Amersfoort
2023-02-06
Active, closed
A Study of Efficacy and Safety of Ianalumab Versus Placebo in Addition to Eltrombopag in Primary Immune Thrombocytopenia Patients Who Failed Steroids
NCT05653219Primary Immune Thrombocytopenia
DrugsEltrombopag·Ianalumab
Novartis Pharmaceuticals
Phase 3
152
Leiden, Utrecht
2023-02-02
By invitation
Oral Immunotherapy in Young Children With Food Allergy
NCT05738798Food Allergy
Deventer Ziekenhuis
Not applicable
500
Deventer, Amsterdam, Delft, Groningen
2023-02-01
Recruiting
Safe Stop Ipilimumab-nivolumab (IPI-NIVO) Trial
NCT05652673Melanoma Stage IV, Melanoma Stage III, Immunotherapy, Toxicity, Drug
DrugNivolumab
Erasmus Medical Center
Not applicable
80
Rotterdam
2023-02-01
Recruiting
Prediction Models for Complications After CRT in Esophageal Cancer
NCT06366828The Aim of This Project is to Develop and Validate NTCP-models for Complications After nCRT (and Surgical Resection)
University Medical Center Groningen
Observational
2,000
Nijmegen, Maastricht, Amsterdam, Rotterdam, Delft, Groningen, Heerlen, Utrecht
2023-02-01
Recruiting
Association Between Venous Excess Ultrasound Grading System and Acute Kidney Injury in the ICU Population
NCT06585722Fluid Overload, Kidney Injury, Make-30
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Observational
136
Amsterdam
2023-02-01
Active, closed
A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - REAL 9
NCT05723835SGA, Turner Syndrome, Noonan Syndrome, ISS
DrugSomapacitan
Novo Nordisk A/S
Phase 3
47
Rotterdam
2023-02-01
Recruiting
Ototoxicity in Patients With MoM Hip Bearings
NCT06885411Ototoxic Hearing Loss, Cobalt Poisoning, Chromium Causing Toxic Effect, Arthroplasty Complications
Reinier Haga Orthopedisch Centrum
Observational
200
Delft
2023-02-01
Recruiting
Expertise Asthma COPD Program with Digital Support
NCT05831566Asthma
Franciscus Gasthuis
Phase 3
138
Rotterdam
2023-01-31
Recruiting
Signal TrAnsduction Pathway Activity Analysis in OVarian cancER
NCT03458221Recurrent Ovarian Cancer, Signal Transduction Pathway Deregulation, Therapy-Associated Cancer
Gynaecologisch Oncologisch Centrum Zuid
Phase 2/3
148
Nijmegen, Eindhoven, Breda, Maastricht, Rotterdam, Tilburg
2023-01-31
Recruiting
Immune Checkpoint Inhibitor Associated Cardiovascular Adverse Events in Patients With Cancer
NCT06519292Cardiovascular Diseases, Arterial Thrombosis, Myocardial Infarction, Stroke
Hanneke W. M. van Laarhoven
Observational
214
Amsterdam
2023-01-25
Recruiting
Technical Evaluation of Commercial IMUs Within Clinical Gait Analysis
NCT05751408Gait Analysis
Roessingh Research and Development
Observational
40
Enschede
2023-01-25
Recruiting
FMRI-neurofeedback in Depression
NCT05640089Depression, Unipolar
Maastricht University Medical Center
Not applicable
120
Maastricht
2023-01-25
Recruiting
ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)
NCT05580562H3 K27M, Glioma
DrugDordaviprone
Jazz Pharmaceuticals
Phase 3
510
Rotterdam, Utrecht
2023-01-23
Recruiting
Generation R Next - Optimaal Opgroeien
NCT05870878Pregnancy Early, Outcome, Adverse Birth, Lifestyle Factors, Preconception Care
Erasmus Medical Center
Not applicable
1,750
Rotterdam
2023-01-19
Recruiting
Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)
NCT05587712Pulmonary Arterial Hypertension
DrugSotatercept
Merck Sharp & Dohme LLC
Phase 2
42
Groningen
2023-01-19
Recruiting
Predictors of Weight Loss and Metabolic Health After Bariatric Surgery
NCT05987631Obesity, Morbid, Insulin Sensitivity, Bariatric Surgery Candidate, Feeding Behavior
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Observational
1,200
Gouda, The Hague, Nieuwegein
2023-01-19
Recruiting
National PROspective Infrastructure for Renal Cell Carcinoma (PRO-RCC)
NCT05326620Renal Cancer, Renal Cell Carcinoma, Renal Cell Cancer Metastatic
PROspective Renal Cancer Cohort Foundation
Observational
2,000
Amsterdam, 's-Hertogenbosch, Amersfoort, Apeldoorn, Arnhem, Breda, Deventer, Dordrecht
2023-01-19
Active, closed
A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults With Multifocal Motor Neuropathy
NCT05405361Multifocal Motor Neuropathy (MMN)
DrugEmpasiprubart
argenx
Phase 2
51
Utrecht
2023-01-18
Recruiting
WHIte MAtter Hyperintensity Shape and Glymphatics
NCT06010511Cerebral Small Vessel Diseases, Dementia, Mixed, Dementia, Vascular, Mild Cognitive Impairment
Leiden University Medical Center
Observational
50
Leiden
2023-01-18
Recruiting
EMR Versus ESD for Barrett's Neoplasia
NCT05276791Barretts Esophagus With Dysplasia, Barrett Adenocarcinoma, Esophageal Cancer
St. Antonius Hospital
Not applicable
331
Amsterdam, Eindhoven, Groningen, Nieuwegein, Rotterdam, Utrecht
2023-01-17
Active, closed
ABTECT - Maintenance
NCT05535946Ulcerative Colitis
DrugObefazimod
Abivax S.A.
Phase 3
1,116
Amsterdam, Geleen, Nijmegen, Rotterdam, Tilburg, Uden, Utrecht
2023-01-16
Active, closed
C2 CryoBalloon™ 180 Ablation System Dose De-escalation Study.
NCT03311451Barrett Esophagus
Merit Medical Systems, Inc.
Not applicable
62
Amsterdam, Eindhoven, Groningen, Rotterdam, Utrecht, Nieuwegein
2023-01-16
Recruiting
Ablation With Confirmation of Colorectal Liver Metastases (ACCLAIM)
NCT05265169Colorectal Liver Metastases
Society of Interventional Oncology
Not applicable
275
Amsterdam
2023-01-13
Active, closed
Single and Repeat Doses of DMT in Healthy Subjects
NCT05559931Stroke
DrugN,N-Dimethyltryptamine
Algernon Pharmaceuticals
Phase 1
60
Leiden
2023-01-13
Recruiting
The Spine PROMCO Study
NCT05963815Lumbar Disc Herniation, Spondylolisthesis, Spinal Stenosis
Park Medical centrum
Observational
4,000
Rotterdam
2023-01-13
Recruiting
FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3
NCT05614739Urinary Bladder Neoplasms, Neoplasm Metastasis, Ureteral Neoplasms
DrugsVepugratinib·Digoxin·Rosuvastatin·Enfortumab Vedotin
Eli Lilly and Company
Phase 1
677
GE Rotterdam
2023-01-12
Active, closed
Proteomics and Genomics Combined With CT to Predict CVD
NCT05800093Coronary Artery Disease Progression
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Observational
310
Amsterdam
2023-01-12
Active, closed
First in Human Study of IMGN151 in Recurrent Gynaecological Cancers
NCT05527184Endometrial Cancer, High Grade Serous Adenocarcinoma of Ovary, Primary Peritoneal Carcinoma, Fallopian Tube Cancer
DrugIMGN151
AbbVie
Phase 1
256
Rotterdam, Groningen, Utrecht
2023-01-11
Active, closed
Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07)
NCT05555732Metastatic Non Small Cell Lung Cancer
DrugsDatopotamab Deruxtecan·Pemetrexed·Keytruda·Cisplatin
Daiichi Sankyo
Phase 3
1,170
's-Hertogenbosch, Breda, Leiden
2023-01-11
Recruiting
What is the Optimal Antithrombotic Strategy in Patients With Atrial Fibrillation Undergoing PCI?
NCT04436978Acute Coronary Syndrome, Myocardial Infarction, Atrial Fibrillation, Atrial Flutter
St. Antonius Hospital
Phase 4
2,000
Alkmaar, Amsterdam, Eindhoven, Emmen, Heerlen, Hilversum, Nieuwegein, The Hague
2023-01-11
Active, closed
A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (SUCCESSOR-2)
NCT05552976Relapsed or Refractory Multiple Myeloma
DrugsMezigdomide·Carfilzomib·Dexamethasone
Bristol-Myers Squibb
Phase 3
606
Breda, Enschede
2023-01-10
Recruiting
The Role of the Tumor Molecular Profile (CMS), UGT1A1 Genotype and Beta-glucuronidase Activity of the Intestinal Microbiota for Treatment Efficiency, Toxicity, Survival and Quality of Life in Patients With Metastatic or Unresectable Colorectal Cancer During Irinotecan-based Systemic Treatment
NCT05655780Colorectal Neoplasms
Maastricht University Medical Center
Observational
104
Maastricht
2023-01-09
Active, closed
Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1
NCT05680818Autosomal Dominant Hypocalcemia (ADH)
DrugEncaleret
Calcilytix Therapeutics, Inc., a BridgeBio company
Phase 3
67
Rotterdam
2023-01-06
Recruiting
Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare
NCT05658575Acute Gout Flare, Gout Attack, Gout Flare, Gouty Arthritis
DrugDapansutrile
Olatec Therapeutics, Inc.
Phase 2/3
300
Amsterdam, Maastricht, Venlo
2023-01-06
Recruiting
Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
NCT05378347Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder), Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder)
Medtronic Cardiovascular
Not applicable
600
Arnhem, Amsterdam, Eindhoven, Rotterdam
2023-01-05
Active, closed
Anti-PD-1 Re-challenge After Immune Priming by Ipilimumab and Immune Boosting by Radiotherapy in Advanced NSCLC
NCT05401786Carcinoma, Non-Small-Cell Lung
DrugsCemiplimab·Ipilimumab
The Netherlands Cancer Institute
Phase 2
54
Amsterdam
2023-01-03
Active, closed
Study of XL092 + Nivolumab vs Sunitinib in Subjects With Advanced or Metastatic Non-Clear Cell Renal Cell Carcinoma
NCT05678673Non-Clear Cell Renal Cell Carcinoma
DrugsSutent·Zanzalintinib·Opdivo·Nivolumab
Exelixis
Phase 3
317
Eindhoven
2023-01-01
Recruiting
The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)
NCT06146725Glioblastoma, Glioblastoma, IDH-wildtype, Glioblastoma Multiforme, Glioblastoma Multiforme, Adult
Jasper Gerritsen
Observational
564
Rotterdam, The Hague
2023-01-01
Recruiting
The COllaborative Neonatal Network for the First CPAM Trial
NCT05701514Congenital Pulmonary Airway Malformation
Erasmus Medical Center
Not applicable
176
Nijmegen, Rotterdam
2023-01-01
Not yet open
Biopsy Versus Resection in Elderly Glioblastoma Patients. A Prospective Cohort Study.
NCT05641220Glioblastoma
Erasmus Medical Center
Observational
325
Alkmaar, Enschede, Maastricht, Rotterdam, The Hague, Tilburg
2023-01-01
Recruiting
The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma
NCT06273176Glioblastoma, IDH-wildtype, Glioblastoma, Glioblastoma Multiforme of Brain, Astrocytoma, Malignant
Erasmus Medical Center
Observational
225
Rotterdam, The Hague
2023-01-01
Recruiting
NEO- and Adjuvant Targeted Therapy in Braf-mutated Anaplastic Cancer of the Thyroid (NEO-ATACT Study)
NCT06079333Anaplastic Thyroid Cancer
DrugDabrafenib/trametinib
Leiden University Medical Center
Phase 2
20
Leiden
2023-01-01
Recruiting
The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)
NCT06283927Glioblastoma, Glioblastoma Multiforme, Glioblastoma, IDH-wildtype, Glioblastoma Multiforme of Brain
DrugsLomustine·Temozolomide
Jasper Gerritsen
Observational
464
Rotterdam, The Hague
2023-01-01
Recruiting
Predict Arrhythmia Risk Using Intelligent Software
NCT07792694Cardiac Arrhythmias, Acute Myocardial Infarction (AMI), Ventricular Tachycardia (VT), Ventricular Fibrillation
Catharina Ziekenhuis Eindhoven
Observational
3,000
Eindhoven
2023-01-01
Active, closed
Multi-Site Eating Disorder Prevention Program for Type 1 Diabetes
NCT05399446Type 1 Diabetes, Eating Disorders
Oslo University Hospital
Not applicable
280
Amsterdam
2023-01-01
Recruiting
Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry
NCT06932081Adult Congenital Heart Disease, Congenital Heart Disease, Systemic Right Ventricle, Transposition of the Great Arteries
Leiden University Medical Center
Observational
400
Leiden, Amsterdam, Utrecht
2023-01-01
Recruiting
Long-term Outcomes After Prolonged Dual Hypothermic Oxygenated Machine Perfusion of Donor Livers (DHOPEPROLONG)
NCT05680246Liver Transplantation
University Medical Center Groningen
Observational
500
Groningen
2023-01-01
Recruiting
The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203)
NCT06146738Glioblastoma, Glioblastoma Multiforme, Glioblastoma, IDH-wildtype, Glioblastoma Multiforme, Adult
Jasper Gerritsen
Observational
1,015
Rotterdam, The Hague
2023-01-01
Recruiting
International Leukemia Target Board
NCT05270096Relapsed Hematologic Malignancy, Refractory Hematologic Malignancy
Princess Maxima Center for Pediatric Oncology
Observational
600
Utrecht
2022-12-31
Active, closed
A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
NCT05595642Chronic Obstructive Pulmonary Disease (COPD)
DrugAstegolimab
Hoffmann-La Roche
Phase 3
1,290
Amersfoort, Groningen, Heerlen
2022-12-29
By invitation
Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema
NCT05396105Hereditary Angioedema, Hereditary Angioedema Type I, Hereditary Angioedema Type II, Hereditary Angioedema Types I and II
DrugDeucrictibant
Pharvaris Netherlands B.V.
Phase 2/3
150
Amsterdam
2022-12-28
Active, closed
Phase 3, Double-blind, Randomized, Placebo-controlled Trial to Evaluate the Efficacy and Safety of AR1001 in Participants With Early Alzheimer's Disease (Polaris-AD)
NCT05531526Alzheimer Disease
AriBio Co., Ltd.
Phase 3
1,535
's-Hertogenbosch, Amsterdam, Breda, Zwolle
2022-12-23
Active, closed
Pembrolizumab for Locally Advanced, Irresectable, Non-metastatic dMMR Colorectal Cancers
NCT05131919Colorectal Cancer
DrugsKeytruda·Pembrolizumab
The Netherlands Cancer Institute
Phase 2
25
Amsterdam
2022-12-22
Active, closed
Colchicine and Inflammation in Aortic Stenosis
NCT05162742Aortic Valve Disease, Aortic Valve Stenosis, Aortic Valve Calcification, Inflammation
DrugColchicine
Radboud University Medical Center
Phase 3
150
Nijmegen
2022-12-22
Recruiting
JAK Inhibition in Ulcerative Colitis
NCT05456412Colitis, Ulcerative
Leiden University Medical Center
Not applicable
60
Leiden
2022-12-20
Recruiting
Study to Determine the Safety and Pharmacokinetics of DO-2 in Patients With Advanced or Refractory Solid Tumours
NCT05752552Adult Solid Tumor, Advanced Solid Tumor, Refractory Tumor, Non-small Cell Lung Cancer
DeuterOncology
Phase 1
55
Nijmegen, Rotterdam
2022-12-20
Active, closed
Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 in Clinical Trials
NCT05335876Spinal Muscular Atrophy (SMA)
DrugZolgensma
Novartis Pharmaceuticals
Phase 3
20
Utrecht
2022-12-19
Recruiting
Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER
NCT05640999Endometrial Cancer
Canadian Cancer Trials Group
Phase 2
393
Arnhem, Maastricht, Eindhoven, The Hague, Leiden, Rotterdam
2022-12-19
Active, closed
MAD Trial: Myopia Atropine Dose
NCT05667454Progressive Myopia
Erasmus Medical Center
Phase 3
550
Almere Stad, Amsterdam, Delft, Deventer, Dordrecht, Ede, Goes, Heerenveen
2022-12-19
Active, closed
A Study Evaluating the Safety and Tolerability of QRL-201 in ALS
NCT05633459Amyotrophic Lateral Sclerosis
QurAlis Corporation
Phase 1
69
Utrecht
2022-12-16
Active, closed
EASYII - E-tegra Stent Graft System - Imaging Cohort
NCT05586503Vascular Aneurysm
JOTEC GmbH
Not applicable
25
Amersfoort, Arnhem, Enschede, Heerlen
2022-12-16
Active, closed
ROSA Knee System vs Conventional Total Knee Arthroplasty
NCT05685693Knee Osteoarthritis
Zuyderland Medisch Centrum
Not applicable
150
Sittard
2022-12-16
Recruiting
Interfant-21 Treatment Protocol for Infants Under 1 Year With KMT2A-rearranged ALL or Mixed Phenotype Acute Leukemia
NCT05327894Acute Lymphoblastic Leukemia, Mixed Phenotype Acute Leukemia
DrugBlinatumomab
Princess Maxima Center for Pediatric Oncology
Phase 3
160
Utrecht
2022-12-15
Active, closed
Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial
NCT05581303Atherosclerotic Cardiovascular Disease
DrugOlpasiran
Amgen
Phase 3
7,297
Amersfoort, Amsterdam, Apeldoorn, Arnhem, Bergen op Zoom, Breda, Delft, Deventer
2022-12-14
Recruiting
Triple Therapy Convenience by the Use of One or Multiple Inhalers and Digital Support in Chronic Obstructive Pulmonary Disease
NCT05495698Copd, Adherence, Medication
DrugTrimbow
Franciscus Gasthuis
Not applicable
300
Rotterdam
2022-12-13
Recruiting
Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease
NCT05650229Primary Mitochondrial Disease
DrugNapazimone
Pharming Technologies B.V.
Phase 2
180
Nijmegen
2022-12-13
Active, closed
CORE-OLE: A Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (SHTG)
NCT05681351Severe Hypertriglyceridemia
DrugOlezarsen
Ionis Pharmaceuticals, Inc.
Phase 3
885
Amsterdam, Apeldoorn, Arnhem, Dirksland, Ede, Hoogeveen, Nijmegen, Rotterdam
2022-12-13
Active, closed
A Phase 1/2 Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Glanzmann Thrombasthenia
NCT06211634Glanzmann Thrombasthenia
Hemab ApS
Phase 1/2
57
Utrecht
2022-12-13
By invitation
Evaluating Edge-to-edge Transcatheter Tricuspid Valve Repair in Patients With Severe Symptomatic Tricuspid Regurgitation
NCT05628779Tricuspid Valve Regurgitation, Nonrheumatic, Cardiac Catheterization, Heart Failure, Right Sided, Valve Regurgitation, Tricuspid
St. Antonius Hospital
Not applicable
150
Amsterdam, Groningen, Leiden, Maastricht, Nieuwegein, Rotterdam
2022-12-12
Recruiting
Prediction of Surgical Resectability After FOLFIRINOX Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Cancer: the Role of Diffusion Weighted Magnetic Resonance Imaging, Radiomics and Liquid Biopsy (PeRFormanCe Trial)
NCT05298722Pancreatic Cancer
University Hospital, Ghent
Not applicable
45
Terneuzen
2022-12-12
Recruiting
Impact of Peri-operative tEstosterone Levels on oNcological and Functional Outcomes in RadiCal prostatEctomy
NCT04833426Prostatic Neoplasms, Hypogonadism, Testosterone Deficiency
DrugTestosterone
Canisius-Wilhelmina Hospital
Phase 3
140
Amsterdam, Arnhem, Eindhoven, Emmen, Heerlen, Nieuwegein, Nijmegen, Veldhoven
2022-12-12
Active, closed
Aronia, Cognition, and Eye Health (ACE)
NCT05683002Cognitive Function
Maastricht University Medical Center
Not applicable
44
Maastricht
2022-12-08
Active, closed
Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation.
NCT05445843Locally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation
DrugJDQ443
Novartis Pharmaceuticals
Phase 2
95
Breda, Leeuwarden
2022-12-06
Active, closed
SerUM Markers in MERkel Cell Carcinoma Patients: a Longitudinal moniTorIng Study for optiMization of European Guidelines
NCT04705389Merkel Cell Carcinoma
University Hospital, Tours
Not applicable
35
Maastricht
2022-12-05
Active, closed
Intercorporal Bone Graft Measurement Study
NCT05565456Spondylolisthesis, Spinal Fusion
Rijnstate Hospital
Observational
30
Arnhem
2022-12-02
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Dutch investigative site. Derived from ClinicalTrials.gov. Retrieved 28 September 2026. https://priyalifescience.com/clinical-trials-netherlands?page=20

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Netherlands and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 3,203 studies in total at the last sync on 26 Sep 2026, 19:48 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

How many clinical trials are recruiting in Netherlands?

1,832 of the 3,203 studies in this register are recruiting new participants as of the 26 Sep 2026, 19:48 UTC sync. A further 189 have not yet opened recruitment, 1,068 are active but closed to new participants, and 114 are enrolling by invitation only. Eligibility for any study is decided by its study team.

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Browse trials by condition

Breast Cancer (63) Prostate Cancer (45) Heart Failure (40) Coronary Artery Disease (37) Multiple Myeloma (37) Atrial Fibrillation (27) Carcinoma, Non-Small-Cell Lung (26) Cancer (25) Crohn's Disease (23) Glioblastoma (23) Obesity (22) Colorectal Cancer (22) Aortic Valve Stenosis (21) Cardiovascular Diseases (21) Non-Small Cell Lung Cancer (20)
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Browse trials by site location

Amsterdam (1240) Rotterdam (867) Groningen (601) Nijmegen (559) Utrecht (541) Maastricht (424) Leiden (386) Eindhoven (207) Arnhem (187) Breda (173) Nieuwegein (155) The Hague (123) 's-Hertogenbosch (117) Enschede (111) Zwolle (110)
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.