Brief-intensive CBT Versus Once-weekly CBT in Anxiety-related Disorders

Condition(s) studied

Investigational drug(s) / intervention(s)

Cognitive behavioral therapy (CBT): The intervention is brief-intensive, guided exposure therapy and consists of 16 sessions exposure therapy, spread over 4 half-days in 2 weeks plus 4 follow-up sessions within 3 months.

Study summary

The goal of this clinical trial is to compare brief-intensive cognitive-behaviour therapy (CBT) with regular weekly CBT in people with anxiety-related disorders.

The main question to answer is: will brief-intensive CBT improve functioning (work, family, social) more and faster than does regular weekly CBT?

Participants will be asked to follow CBT treatment (20 sessions of 45 minutes in both conditions), and participate in 7 measurements with a total duration of 5 hours over 1 year.

Researchers will compare:

* Brief-intensive CBT: 16 sessions in 2 weeks + 4 follow-up sessions within 3 months
* Regular CBT with 20 weekly sessions in 6 months

Eligibility

Primary outcome measure(s)

• Area Under the health and disability Curve at 6 months — baseline, 2 weeks, 4 weeks, 2 months, 3 months, 6 months
  The 'area under the curve' for health and disability is based on the 36-item self-report World Health Organisation Disability Assessment Schedule (WHODAS 2.0). The WHODAS 2.0 captures the level of functioning in six domains of life: Cognition, Mobility, Self-care, Getting along, Life activities, Participation. Possible total scores of the items across all domains range 0 - 100. Lower scores indicate less disability.

Trial sites (6)

More Amsterdam UMC, location VUmc trials in the Netherlands

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