Postprandial Glucose Levels, Gut Microbiota and Supplementation With Functional Foods in Adults

Condition(s) studied

Investigational drug(s) / intervention(s)

Dietary Supplement: A package containing a mix of functional foods: Participants will be provided with a nutritional strategy based on functional foods to use over the 2 week trial. These will be nopal, chía seeds, inulin, soy protein, agave extract and genistein.

Study summary

This is a clinical study with participants over 18 years of age that meet the selection criteria. This will be 42-day study divided into three phases of 14 days each: 14 days without intervention, 14 days with intervention with functional foods and 14 days without intervention again. With the objective of assess the changes in the postprandial glycemic responses through the gut microbiota and urine metabolites.

Eligibility

Primary outcome measure(s)

• Changes in postprandial glucose responses — 6 weeks
  Postprandial glucose concentrations (mmol/L). The incremental area under the curve will be calculated and expressed as mmol\*minutes/litre.
• Changes in diversity analysis of intestinal microbiota with and without intervention with functional foods — 6 weeks
  Based on the gene and species composition of each sample, the Chao1 and Shannon indexes, as well as the observed operational taxonomic units, will be calculated in order to identify the differences in gene and species diversity for each group

Trial sites (1)

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