Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact
Clinical Trials in Mexico / NCT03927833
Active, not recruiting Not applicable

Cycled Phototherapy

NCT03927833 · tracked via the Priya Life Science Mexico tracker
Sponsor
NICHD Neonatal Research Network
Phase
Not applicable
Started
2020-07-16
Last updated
2026-06-17

Condition(s) studied

Hyper BilirubinemiaPremature Infant

Investigational drug(s) / intervention(s)

Phototherapy lights

Phototherapy lights: Phototherapy lights used continuously or timed, following an algorithm based upon TSB levels.

Study summary

Cycled phototherapy (PT) is likely to increase survival over that with continuous PT among extremely premature infants (\< 750 g BW or \<27 weeks GA).

Eligibility

Sex
ALL
Min age
22 Weeks
Max age
27 Weeks
Healthy volunteers
No
Inclusion Criteria: 1. Infants is inborn 2. Infant is ≤ 750 grams at birth and/or \< 27 weeks gestation at birth by best OB estimate 3. Infant is 12-36 hours of age. Exclusion Criteria: 1. Unable to enroll infant by 36 hours of age 2. Previous phototherapy 3. Known hemolytic disease 4. TSB reported as \>6.0 mg/dL before 12 hours age 5. Major anomaly 6. Overt nonbacterial infection 7. Infant is likely to expire soon: Limiting or withdrawal of intensive care is being recommended to the parents, the parents are requesting withdrawal of care, or the pH is \< 6.80 or persistent bradycardia with hypoxemia for \>2h.

Primary outcome measure(s)

  • Number of participants survival to discharge — Birth to hospital discharge, up to 120 days of life
    Number of Participants discharged from hospital alive, after birth.

Trial sites (19)

FacilityCityRegionStatus
University of Alabama at Birmingham Birmingham Alabama
Stanford University Palo Alto California
Sharp Mary Birch Hospital for Women & Newborns San Diego California
Emory University Atlanta Georgia
Northwestern Lurie Children's Hospital of Chicago Chicago Illinois
University of Iowa Iowa City Iowa
University of Mississippi Medical Center - Children's of Mississippi Jackson Mississippi
University of New Mexico Albuquerque New Mexico
University of Rochester Rochester New York
RTI International Durham North Carolina
Duke University Durham North Carolina
Cincinnati Children's Medical Center Cincinnati Ohio
Case Western Reserve University, Rainbow Babies and Children's Hospital Cleveland Ohio
Research Institute at Nationwide Children's Hospital Columbus Ohio
Univeristy of Pennsylvania Philadelphia Pennsylvania
Brown University - Women and Infants Hospital of Rhode Island Providence Rhode Island
University of Texas Southwestern Medical Center at Dallas Dallas Texas
University of Texas Health Science Center at Houston Houston Texas
University of Utah Salt Lake City Utah

More NICHD Neonatal Research Network trials in Mexico

Milrinone for Prevention of Post-ligation Cardiac Syndrome Trial Recruiting
Neonatal Platelet Transfusion Threshold Trial Recruiting
Follow-up Visit of High Risk Infants Recruiting
Continued Pressure for Alveolar Protection (CPAP Trial) Recruiting
The Budesonide in Babies (BiB) Trial Active, not recruiting

Other trials for the same condition

Effects of Oral Stimulation Performed by Parents to Improve Sucking in Neonates Hospitalized in the NICU Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT03927833 on ClinicalTrials.gov ↗ ← All trials in Mexico