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Evidence-Based Nursing to Reduce Adverse Events Regarding Ventilator Associated Pneumonia, Pressure Injuries and Central Line Bloodstream Infection in Intensive Care Unit in Bangladesh

NCT07299799 · tracked via the Priya Life Science Japan tracker
Phase
Not applicable
Started
2026-02-15
Last updated
2026-02-11

Condition(s) studied

Ventilator Acquired PneumoniaCentral Line Associated Blood Stream Infections (CLABSI)Pressure Ulcer (PU)Medical Device Related Pressure Ulcer (MDRPU)

Investigational drug(s) / intervention(s)

Education with EBPThis is a pre- and post- quasi-experimental study.

Education with EBP: Trial 1: Nurse's EBP training ( VAP, PU, MDRPU, CLABSI management), online lecture, 2 hours lecture and 3 hours skill training for nurses training. Trail 1 we use advanced equipment necessary for EBP implementation for VAP, PU, MDRPU and CLABSI management, and EBP-trained nurses implementation for all this management.

This is a pre- and post- quasi-experimental study.: We will use advanced equipment and implement EBP (VAP, PU, MDRPU and CLABSI management) for patients by trained nurses and check the outcome of the patients. We will compare pre and post findings for this study.

Study summary

Quality of care is crucial for preventing adverse events such as infection in the intensive care units (ICUs). The most common ICU-acquired infections include pneumonia such as Ventilator Associated Pneumonia (VAP), Pressure Ulcer (PU), Medical Device Related Pressure Ulcer (MDRPU), and Central Line-Associated Bloodstream Infection (CLABSI). VAP, PU, and MDRPU are significant indicators of the quality of care, while CLABSI is a critical marker of healthcare quality in ICUs, as it is largely preventable through strict adherence to infection control protocols.

VAP is a lung infection that occurs in patients receiving mechanical ventilation for more than 48 hours. A PU is defined as localized damage to the skin or underlying tissue caused solely by pressure, while MDRPUs may also result from friction or pressure from medical devices or other objects. CLABSI is a severe infection caused by improperly inserted or maintained central venous catheters, which underscores the need for stringent catheter management protocols.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Trial 1 \& 2- Inclusion Criteria: Nurse * who is a registered nurse in Bangladesh. * who agrees to participate in this study and the EBP training. * who will stay at the ICU for 6 months. Patient * Irrespective of age and sex, participants must be at least 18 years old * Legal guardian of a patient consent to participation in the study Exclusion Criteria: Nurse * Who will not directly involve patient care in ICU. Patient * No exclusion criteria

Primary outcome measure(s)

  • The nurse's skill related to the PU, MDRPU and CLABSI total score measured by the researcher-developed checklist — 6 month data collection and total time frame of this study 16 months
    1\. The nurse's skill and knowledge related to the PU, MDRPU and CLABSI checklist. Researcher developed checklist, 50 items with 0: not correct/did not do, 1: partially correct, 2: correct. Score range 0-114.
  • Incidence rates of PU, MDRPU and CLABSI. — 2 month for data collection and total time frame 16 months.
    The incidence rate of PU was calculated as the number of newly developed pressure ulcers after hospitalization per 1000 person-days at risk. The incidence rate of MDRPU was calculated as the number of newly developed MDRPU cases per 1000 patients assessed. The incidence rate of CLABSI was calculated as the number of CLABSI cases per 1000 central line-days. Data will be collected: Patients' demographic data (age, sex, occupation etc.) Medical past and current history (diagnosis, treatment, medication, hospitalization). Reasons and date to be admitted to ICU. Treatment in ICU. Daily laboratory data taken in ICU. Daily biological data including vital signs. Results of patients' stay during ICU. Diagnosis of PU, MDRPU and CLABSI included of this list.

Trial sites (2)

FacilityCityRegionStatus
Dhaka Medical College Hospital Dhaka Dhaka Division
Hiroshima University Hiroshima Hiroshima City
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07299799 on ClinicalTrials.gov ↗ ← All trials in Japan