Clinical Trials in Japan / NCT06622941
Recruiting
Phase 2
Study to ONO-4538 in Patients With Rhabdoid Tumor
NCT06622941 · tracked via the Priya Life Science Japan tracker
Condition(s) studied
Rhabdoid Tumor
Study summary
Investigate the efficacy and safety of ONO-4538 for the treatment of rhabdoid Tumors
Eligibility
Inclusion Criteria:
1. Gender: Not specified
2. Age (at the time of consent): 1 year or older
3. Patients who are refractory or intolerant to one or more regimens of chemotherapy for rhabdoid Tumors
4. Patients with advanced or recurrent rhabdoid Tumors not eligible for curative resection
Exclusion Criteria:
1. Patients with a history of active concurrent malignancy or complications
2. Patients with spinal lesions expected to require radiation therapy or surgical intervention during the trial period
3. Patients with concomitant central nervous system disorders other than AT/RT that are inadequately controlled or may lead to discontinuation of the investigational drug
Primary outcome measure(s)
- Objective response rate (ORR) — up to 4.5 years
Trial sites (14)
| Facility | City | Region | Status |
|---|---|---|---|
| Nagoya University Hospital | Nagoya | Aichi-ken | Recruiting |
| Hokkaido University Hospital | Sapporo | Hokkaido | Recruiting |
| Hyogo Prefectural Kobe Children's Hospital | Kobe | Hyōgo | Recruiting |
| Osaka City General Hospital | Osaka | Osaka | Recruiting |
| National Cancer Center Hospital | Chuo-ku | Tokyo | Recruiting |
| Chiba University Hospital | Chiba | Japan | Recruiting |
| Kyushu University Hospital | Fukuoka | Japan | Not Yet Recruiting |
| Fukushima Medical University Hospital | Fukushima | Japan | Recruiting |
| Hiroshima University Hospital | Hiroshima | Japan | Recruiting |
| Kanazawa University Hospital | Kanazawa | Japan | Recruiting |
| University Hospital, Kyoto Prefectural University of Medicine | Kyoto | Japan | Recruiting |
| Tohoku University Hospital | Miyagi | Japan | Recruiting |
| Niigata University Medical & Dental Hospital | Niigata | Japan | Recruiting |
| National Center for Child Health and Development | Tokyo | Japan | Recruiting |
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Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06622941 on ClinicalTrials.gov ↗ ← All trials in Japan