Ireland
--:--IST
Enrolling by invitation Observational

Minicrush Versus Culotte Stenting in Complex Coronary Bifurcation Lesions:The Multicenter T-REX II Registry

NCT07849335 · tracked via the Priya Life Science Italy tracker
Phase
Observational
Started
2026-09-01
Last updated
2026-09-30

Condition(s) studied

Coronary Artery Disease (CAD)Percutaneous Coronary Intervention (PCI)Bifurcation Coronary Artery Disease

Investigational drug(s) / intervention(s)

Percutaneous Coronary Intervention with Minicrush

Percutaneous Coronary Intervention with Minicrush: The Minicrush and Culotte techniques were performed as upfront two-stent strategies according to standard protocols focusing on minimal side-branch stent protrusion and carina reconstruction, respectively.

Study summary

Percutaneous coronary intervention (PCI) of complex coronary bifurcation lesions frequently requires an upfront two-stent strategy. While the double kissing crush technique has been extensively studied, limited contemporary data are available comparing alternative two-stent approaches, particularly Minicrush and T-stenting and Culotte, in complex bifurcation anatomy. This study aimed to compare procedural characteristics and long-term clinical outcomes of Minicrush versus Culotte stenting techniques in patients undergoing PCI for complex coronary bifurcation lesions.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patients with complex coronary bifurcation lesions according to DEFINITION criteria Exclusion Criteria: * \<18 years * Treatment with other techniques * Non-complex coronary bifurcation lesions

Primary outcome measure(s)

  • Target Lesion Failure (TLF) — From the enrollment to the end of the study at 5 years
    Composite of cardiac death, Target Vessel Myocardial Infarction and Target Lesion Revascularization

Trial sites (1)

FacilityCityRegionStatus
Rivoli Hospital Rivoli Turin
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07849335 on ClinicalTrials.gov ↗ ← All trials in Italy