Ireland
--:--IST
Recruiting Observational

Effects of Obesity on Physical Abilities and Daily Living Activities in Elderly Adults

NCT07614464 · tracked via the Priya Life Science Italy tracker
Phase
Observational
Started
2025-05-29
Last updated
2026-05-29

Condition(s) studied

ObesitySarcopenic Obesity

Investigational drug(s) / intervention(s)

Fitness tests and questionnaires

Fitness tests and questionnaires: Anthropometric measurements, physical fitness tests and daily life questionnaires

Study summary

Obesity is a significant health problem whose prevalence has tripled worldwide in the last fifty years, also involving older people. Older people present sarcopenia, characterized by the progressive loss of muscle mass and strength. Sarcopenia, accompanied by an increase in adipose tissue, causes a specific condition called sarcopenic obesity. The increase in adipose tissue and the decrease in muscle mass determines a reduction in strength and physical abilities necessary to perform everyday activities of daily living in obese older people.

To understand how the condition of excess adipose tissue influences the activities of daily living of older people with obesity, it is necessary to compare the physical abilities, body composition, and results of various motor skills with normal-weight subjects, corrected for sex and age.

Eligibility

Sex
ALL
Min age
65 Years
Max age
—
Healthy volunteers
Accepted
Obese elderly: Inclusion Criteria: * Both sexes * Body Mass Index \> 35 kg/m2 * Age \> 65 years * Hospitalized for a 3-week integrated metabolic rehabilitation program Exclusion Criteria: * Absence of signed informed consent Normal weight elderly: Inclusion Criteria: * Both sexes * Body Mass Index 20-25 kg/m2 * Age \> 65 years * Attendance of healthy lifestyle program in their home town Exclusion Criteria: * Absence of signed informed consent

Primary outcome measure(s)

  • Fat mass — Baseline
    Fat mass as assessed by bioelectrical impedance
  • Lean mass — Baseline
    Lean mass as assessed by bioelectrical impedance
  • Barthel Index — Baseline
    Level of independence in 10 basic daily activities (ADLs) Total score ranges from 0 to 100
  • Handgrip test — Baseline
    Score in kilograms (kg) using a hand dynamometer

Trial sites (1)

FacilityCityRegionStatus
Istituto Auxologico Italiano IRCCS, Site Piancavallo Oggebbio Italy Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07614464 on ClinicalTrials.gov ↗ ← All trials in Italy