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Clinical Trials in Italy / NCT07518069
Recruiting Observational

Genetic and Biohumoral Factors Involved in Menière's Disease and Their Correlation With Phenotypes

NCT07518069 · tracked via the Priya Life Science Italy tracker
Sponsor
IRCCS San Raffaele
Phase
Observational
Started
2025-04-09
Last updated
2026-04-08

Condition(s) studied

VertigoMeniere's DiseaseVestibular Migraine

Investigational drug(s) / intervention(s)

a blood withdrawal will be obtainedblood withdrawal

a blood withdrawal will be obtained: A blood withdrawal will be obtained to assess

blood withdrawal: Genetics of ionic transporters and biohumoral factors related to Meniere's Disease and differences with vestibular migraine subjects

Study summary

Aim of this work was to assess the role of polymorphisms belonging to genes involved in the regulation of ionic homeostasis in Caucasian patients with Ménière Disease (MD) and compare results with a cohort of patients affected by vestibular migraine and a cohort of non vestibular subjects

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: * Patients with definite Menière's Disease according to the criteria of the Barany Society Exclusion Criteria: * surgically treated before the examination or if they had undergone intratympanic therapy with steroids or gentamicin

Primary outcome measure(s)

  • Genetic of ionic transporters — From enrollment to the end of enrollment in december 2027
    Genomic DNA of all cases and controls was extracted from venous blood by standard methods. 36 Single Nucleotide Polymorphisms (SNPs) were genotyped using TaqMan® OpenArray™ Genotyping System (Life Technologies, Foster City, CA). All DNA samples were loaded and amplified according to the manufacturer's instructions.

Trial sites (1)

FacilityCityRegionStatus
IRCCS San Raffaele Milan Italy Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07518069 on ClinicalTrials.gov ↗ ← All trials in Italy