Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide
Clinical Trials in Italy / NCT07508449
Active, not recruiting Not applicable

EXErcise in MIGraine

NCT07508449 · tracked via the Priya Life Science Italy tracker
Sponsor
Centro Universitario Ricerca Interdipartimentale Attivita' Motoria
Phase
Not applicable
Started
2025-02-03
Last updated
2026-04-02

Condition(s) studied

Migraine in Adults

Investigational drug(s) / intervention(s)

exercise program supervised by specialized kinesiologistsStandard neurological visit at the Headache Centre

exercise program supervised by specialized kinesiologists: The duration of the program is 12 weeks, with 2 sessions per week of mixed activities (aerobic exercises + muscle strengthening exercises). Each session lasts about 60 minutes, including a warm-up phase, a central phase and a cool-down phase. In particular, for aerobic exercises, the central phase involves the use of various ergometers (e.g. treadmill and cycle ergometer) and a moderate intensity of training (55-69% of Heart Rate Reserve), while for muscle strengthening exercises will be administered bodyweight exercises, with small tools (e.g. elastic bands, medicine ball, etc.) or with isotonic machines (e.g. lat machines and leg presses), with an initial work intensity of 45-50% of One Repetition Maximum.

Standard neurological visit at the Headache Centre: Participants will be invited to participate a: 1. \- specialist visit at the Headache Centre; 2. a - anthropometric, metabolic, and dietary assessment; 2b - self-administered (via a digital, online, form divided into four parts) and researcher-administered questionnaires; 2c - kinesiological assessment of functional capacities (aerobic capacity, muscle strength and flexibility); 2d - complete postural evaluation (divided into objective, instrumental, functional and neuromotor examination); 2e - traditional/complete gnathological evaluation, according to international diagnostic criteria.

Study summary

The study project aims to implement therapeutic patient education for migraine, promoting improvement in outpatient clinical practice by providing counseling moments specifically dedicated to known health risk factors (sedentary lifestyle, physical inactivity, unhealthy eating habits), thanks to the integration of the skills of Neurology Specialists and those of CURIAMo.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * Migraine with and without aura. * Number of attacks month ≥ 8 and \< 15 for episodic high-frequency patients and ≥ 15 for chronic migraine patients for at least 3 months. * Age 18 to 65 years at screening. * Physical inactivity (defined as insufficient amount of physical activity practiced according to current guidelines, i.e. \<150 min./week). * Ability to walk independently at the time of assessment. Exclusion Criteria: * Age \< 18 years or older than 65 years; * clinical evidence of significant cardiovascular, central nervous system, and musculoskeletal disease that may limit or contraindicate exercise practice. * Failure to give consent to the study.

Primary outcome measure(s)

  • Number of migraine attacks/month and Physical Activity levels — From the time of enrollment and at 6/12 months
    Relationships between lifestyle (in particular Physical Activity levels, and the number of migraine attacks/month

Trial sites (2)

FacilityCityRegionStatus
CURIAMo Perugia PG
Centro Cefalee c/o Ospedale Santa Maria della Misericordia, Azienda Ospedaliera di Perugia Perugia PG

More Centro Universitario Ricerca Interdipartimentale Attivita' Motoria trials in Italy

Interdisciplinary Counselling in DIAbetes Recruiting
Physical Activity, Mediterranean Diet and Maternity Blues: a Multidisciplinary Approach Starting soon
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07508449 on ClinicalTrials.gov ↗ ← All trials in Italy