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Clinical Trials in Italy / NCT07364539
Recruiting Observational

Local Registry of Central Nervous System Infections (ReCeNSI)

NCT07364539 · tracked via the Priya Life Science Italy tracker
Sponsor
Fondazione IRCCS Policlinico San Matteo di Pavia
Phase
Observational
Started
2022-03-04
Last updated
2026-01-23

Condition(s) studied

Central Nervous System (CNS) Infection

Study summary

Central Nervous System (CNS) infections are considered rare conditions but at the same time, they are emergencies whose diagnosis and treatment are time-dependent. They include several clinical syndromes, including meningitis, encephalitis, brain abscesses, and post-surgical meningitis. The classic triad of symptoms includes fever, altered mental status, and neck stiffness, but other common manifestations include nausea and vomiting, cranial nerve dysfunction, skin rash, and seizures. Due to the potentially life-threatening effects on patients, these clinical conditions cannot be underestimated. The CNS includes the brain and spinal cord, surrounded and protected by the meninges and cerebrospinal fluid (CSF). Within the CNS are numerous nuclei responsible for vital functions, as well as more complex intellectual activities.

Eligibility

Sex
ALL
Min age
—
Max age
—
Healthy volunteers
No
* Pazients admitted to the Fondazione IRCSS Policlinico San Matteo * Diagnosis of bacterial meningitis, meningoencephalitis, bacterial CNS infection, viral CNS infection, viral encephalitis, brain abscess, or post-neurosurgical meningitis.

Primary outcome measure(s)

  • To evaluate the outcome in terms of mortality at discharge in patients with CNS infections. — From January 2012

Trial sites (1)

FacilityCityRegionStatus
Fondazione IRCCS Policlinico San Matteo di Pavia Pavia Italia Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07364539 on ClinicalTrials.gov ↗ ← All trials in Italy