Demographic and Interpopulation Variations in Evaluation and Results of TAVI

Condition(s) studied

Investigational drug(s) / intervention(s)

laboratory biomarker analysis: Results of common laboratory tests obtained during routine care in the pre-procedural period (simple blood morphology, creatinine, GFR, NTproBNP). Inflammatory indices - NLR, MLR, PLR

Computed tomography of aortic root and aorta: Results of CT analysis performed as a routine diagnostic examination in the pre-procedural period will be recorded.

Study summary

The aim of the project is to evaluate demographic, clinical, and laboratory variations in patients with aortic stenosis treated with TAVI in different countries. Moreover, the study will evaluate interpopulation differences in aortic root anatomy based on computed tomography analysis.

Eligibility

Primary outcome measure(s)

• Aortic annulus diameter — Baseline
  Aortic annulus diameter in milimeters based on CT image
• Aortic annulus area — Baseline
  Aortic annulus area in squared milimeters based on CT image
• Aortic annulus perimeter — Baseline
  Aortic annulus perimeter in milimeters based on CT image
• Ilio-femoral artery diameter — Baseline
  Ilio-femoral artery diameter in milimeter based on CT image
• Neutrophils measured using whole blood count — Baseline
  This measurement is used to compute ratio of cell types using whole blood count
• Monocytes measured in whole blood count — Baseline
  Number of monocytes identified in blood sample using automatic whole blood count. It is used to compute cell type ratio.
• Lymphocytes measured using whole blood count — Baseline
  This measurement is used to compute ratio of cell types using whole blood count

Trial sites (5)

Other trials for the same condition