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Clinical Trials in Italy / NCT07233941
Recruiting Observational

Neuropsychological Profile Characterization in Patients With Migraine: Cognitive Functioning and Psychological Variables

NCT07233941 · tracked via the Priya Life Science Italy tracker
Sponsor
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Phase
Observational
Started
2025-09-01
Last updated
2026-02-11

Condition(s) studied

MigraineMigraine Disease

Study summary

The overall objective is to define the neuropsychological profile of patients with migraine and evaluate its association with: psychological outcome measures (anxiety-depressive symptoms, pain catastrophizing, excessive worry, and coping strategies); the clinical profile of migraine; the prodromal, ictal, or interictal phase of the migraine attack; pharmacological therapy; and detoxification treatment in patients with migraine associated with medication overuse headache.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * Written informed consent. * Patients aged between 18 and 65 years. * Diagnosis of migraine according to the International Classification of Headache Disorders (ICHD-3) criteria. * Patients with a history of migraine for at least one year, to ensure the stability of the condition. * Stability of ongoing treatment for at least 3 months at baseline. * Understanding of the Italian language. Exclusion Criteria: * Severe medical or psychiatric conditions (depression, schizophrenia, psychosis) documented by specific previous diagnoses. * A history of alcohol or drug abuse. * Primary sensory deficits.

Primary outcome measure(s)

  • Cognitive functioning — 2 years
    Neuropsychological test scores in migraine patients and proportion of participants with cognitive performance significantly different from age- and education-adjusted normative data.

Trial sites (1)

FacilityCityRegionStatus
Fondazione IRCCS Istituto Neurologico Carlo Besta Milan Italy Recruiting

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COMparative Performance of General Purpose Models Recruiting
Longitudinal Study of Ultra-rare Inherited Metabolic and Degenerative Neurological Diseases. Recruiting

Other trials for the same condition

Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects Recruiting
RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatment Recruiting
Efficacy and Safety of Erenumab in Pediatric Participants With Episodic Migraine Active, not recruiting
The Effectiveness of Eptinezumab During a Migraine Attack (the BE-FREE Study) Recruiting
Studio TIARA: Alessitimia ed Emicrania Cronica Enrolling by invitation
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07233941 on ClinicalTrials.gov ↗ ← All trials in Italy