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Clinical Trials in Italy / NCT07155772
Recruiting Not applicable

Feasibility Study on a Prehospital Extracorporeal CardioPulmonary Resuscitation in the Pavia's Province.

NCT07155772 · tracked via the Priya Life Science Italy tracker
Sponsor
Fondazione IRCCS Policlinico San Matteo di Pavia
Phase
Not applicable
Started
2024-11-26
Last updated
2025-09-04

Condition(s) studied

Refractory Cardiac Arrest

Investigational drug(s) / intervention(s)

Extracorporeal CardioPulmonary Resuscitation (eCPR)

Extracorporeal CardioPulmonary Resuscitation (eCPR): The intervention of this study consists of moving the current eCPR program out of the hospital to reduce the time from collapse to ECMO flow (low-flow time).

Study summary

This is a single Center interventional study, assessing the feasibility of a complex treatment strategy where an in-hospital standard care process is applied in an out-of-hospital cardiac arrest.

The objective of this study is to investigate the feasibility of a prehospital eCPR program in the context of the Pavia province in order to reduce the time from cardiac arrest to organ reperfusion with thefarthest aim of improving survival and good neurologic outcomes of patient victims of refractory cardiac arrest.

Eligibility

Sex
ALL
Min age
18 Years
Max age
70 Years
Healthy volunteers
No
Inclusion Criteria: * out-of-hospital cardiac arrest occurred in Pavia province * the age of the patient is between 18 and 70 * witnessed cardiac arrest * CPR started within 5 minutes of the patient's collapse or presence of gasping at the arrival of the ACLS team * eCPR team arrived within 60 minutes of the patient's collapse * etCO2 ≥ 10 mmHg * mechanical chest compression is ongoing * refractory cardiac arrest after at least 15 minutes of ACLS Exclusion Criteria: * Modified Rankin Scale (mRS) ≥ 3 * Advanced COPD or other advanced pulmonary illness * End-stage or metastatic neoplasm

Primary outcome measure(s)

  • number of successful eCPR placed in prehospital settings over patients that meet inclusion criteria — up to 12 months
    Successful cannulation is described as maintaining an ECMO circulatory flow of 40 ml/kg/min or more for at least 5 minutes.

Trial sites (1)

FacilityCityRegionStatus
Fondazione IRCCS Policlinico San Matteo Pavia Pavia Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07155772 on ClinicalTrials.gov ↗ ← All trials in Italy