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Clinical Trials in Italy / NCT06814782
Starting soon Not applicable

Effects of Action Observation Training and Motor Imagery Delivered by Telerehabilitation in Patients with Parkinson's Disease

NCT06814782 · tracked via the Priya Life Science Italy tracker
Sponsor
Istituto Clinico Humanitas
Phase
Not applicable
Started
2025-03-01
Last updated
2025-02-07

Condition(s) studied

Parkinson Disease

Investigational drug(s) / intervention(s)

Action Observation TrainingAction Observation and Motor ImageryExercise

Action Observation Training: Action Observation Training (AOT) consists of patients observing videos of specific movements, followed by practice of those movements

Action Observation and Motor Imagery: Action Observation and Motor Imagery (AOMI) consists of patients observing videos of specific movements, followed by mental rehearsal of those movements

Exercise: After watching a landscape video, patients will have to perform specific postural and balance exercises

Study summary

The goal of this clinical trial is to investigate the efficacy on motor and postural tasks of Action Observation Training (AOT) and Action Observation combined with Motor Imagery (AOMI) delivered by telerehabilitation in patients with Parkinson Disease.

* The primary endpoint will be mobility measured with the Timed Up and Go (TUG) test (differences before and after telerehabilitation treatment period).
* In addition, clinical and functional measures, instrumental analysis of gait and posture, and Magnetic Resonance Imaging (MRI) correlates will be assessed.

Participants will be asked to undergo 24 telerehabilitation sessions, cadenced 3 per week, over an 8-week period. In the two experimental groups (AOT and AOMI), each telerehabilitation session will encompass 4 motor tasks, each containing the observation of a video clip immediately followed by the patient's execution or imagination of the same exercises. Patients in the control group will be instructed to perform the same exercises after watching videos showing landscapes

Eligibility

Sex
ALL
Min age
—
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: * diagnosis of clinically definite PD according to the Movement Disorders Society criteria * Hoehn and Yahr scale \<4 * Montreal Cognitive Assessment, MoCA ≥ 26 * a stable medication regimen for at least 4 weeks. Exclusion Criteria: * Systemic, psychiatric, or other neurological illnesses influencing motor or functional performance * a history of substance abuse influencing cognition or compliance * visual disturbances * head tremor

Primary outcome measure(s)

  • Timed Up and Go test — From enrollment to the end of treatment at 8 weeks
    Patients will be instructed to stand up from a chair, walk 3 meters, turn, and return to sit down. The time taken to complete the task will be recorded.

Trial sites (1)

FacilityCityRegionStatus
Istituto Clinico Humanitas Rozzano Milan

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06814782 on ClinicalTrials.gov ↗ ← All trials in Italy