Clinical Trials in Italy / NCT06804265
Recruiting
Observational
Molecular Biology in the Identification of Pathogens at Reimplantation in the Two-Stage Treatment of Periprosthetic Infections
NCT06804265 · tracked via the Priya Life Science Italy tracker
Condition(s) studied
Periprosthetic Joint Infection (PJI)
Study summary
The goal of this observational study is to measure the diagnostic accuracy of the Multiplex PCR technique in identifying pathogens during the diagnostic stage of resolving pre-implantation infection, in the context of treatment according to two-stage protocol for PJIs. This evaluation will be conducted by comparing the results obtained by Multiplex PCR with those derived from standard culture examination.
Eligibility
Inclusion Criteria:
* Diagnosis of periprosthetic infection of hip, knee, shoulder on primary or already revised implant.
* treatment of infection with two-stage protocol.
* Obtaining informed consent
* Age ≥18 years
Exclusion Criteria:
* Isolates obtained during explantation not included in MULTIPLEX PCR panel
Primary outcome measure(s)
- Accuracy, sensitivity and specificity of the PCR technique in identifying the pathogen responsible for PJIs — up to 100 weeks
comparison with the current diagnostic gold standard, represented by culture examination
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| IRCCS Azienda Ospedaliero-Universitaria di Bologna | Bologna | Italy | Recruiting |
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Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06804265 on ClinicalTrials.gov ↗ ← All trials in Italy