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Clinical Trials in Italy / NCT06773702
Active, not recruiting Observational

Evaluation of Upper Esophageal Sphincter Motor Activity in Patients with Extra Esophageal Reflux Symptoms

NCT06773702 · tracked via the Priya Life Science Italy tracker
Sponsor
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Phase
Observational
Started
2020-03-20
Last updated
2025-01-14

Condition(s) studied

Gastroesophageal Reflux Disease

Investigational drug(s) / intervention(s)

gastroenterology and otolaryngological evaluation

gastroenterology and otolaryngological evaluation: * Gastroenterology evaluation: presence and intensity of esophageal symptoms of gastro esophageal reflux disease, high-resolution esophageal manometry, and 24-hour pH-impedancometry in the absence of PPI therapy. * otolaryngological evaluation: presence and intensity of laryngopharyngeal reflux symptoms, laryngoscopy.

Study summary

To evaluate the presence of motor changes of the upper esophageal sphincter detectable by high-resolution manometry in patients with oropharyngeal symptoms referable to extra-esophageal reflux manifestations.

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion criteria. * Age between 18 and 80 years. * Patients with laryngopharyngeal reflux symptoms. * Obtaining informed consent. Exclusion criteria. * Patients with tobacco habit. * Patients with occupational exposure to irritants (artisans and industrial workers).

Primary outcome measure(s)

  • Evaluate the presence of motor changes of the upper esophageal sphincter detectable on high-resolution manometry in patients with oropharyngeal symptoms referable to extra-esophageal reflux manifestations. — 1 year
    Evaluate the presence of motor changes of the upper esophageal sphincter detectable on high-resolution manometry in patients with oropharyngeal symptoms referable to extra-esophageal reflux manifestations.

Trial sites (1)

FacilityCityRegionStatus
IRCCS Azienda Ospedaliero-Universitaria di Bologna Bologna Bologna

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06773702 on ClinicalTrials.gov ↗ ← All trials in Italy