Medication Related Osteonecrosis of the Jaws (MRONJ) in a Cohort of Patients Treated by Antiresorptive Drugs
Condition(s) studied
Investigational drug(s) / intervention(s)
Dental management: The oral conditions of the included patients will be evaluated at baseline. When indicated, dental extractions will be performed before the beginning of Antiresorptive Therapy. Patients will then receive a six-months intervals follow-up, during which primary and secondary prevention of dental diseases will be performed.
Study summary
The objective of this prospective observational study is to investigate the incidence of Medication Related Osteonecrosis of the Jaws (MRONJ) in patients receiving antiresorptive drugs for oncohematologic reasons during a 5-year follow-up. Secondary objectives are to compare the different antiresorptive drugs in relation to the incidence of MRONJ and to identify any systemic as well as local risk factors.
Eligibility
Primary outcome measure(s)
- Medication Related OsteoNecrosis of the Jaws — Five years after the beginning of AR therapy
Incidence of Medication Related OsteoNecrosis of the Jaws
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Cosimo Rupe | Roma | Italy | Recruiting |
More Catholic University of the Sacred Heart trials in Italy
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06457776 on ClinicalTrials.gov ↗ ← All trials in Italy