Role of Cardiac AngioMR in Diagnosis of Cardiac and Vascular Anomalies in Adult Patients with Turner Syndrome

Condition(s) studied

Investigational drug(s) / intervention(s)

imaging: cardiac angioMR

Study summary

Considering the high prevalence of cardiovascular disease in Turner syndrome patients, noninvasive cardiac imaging is crucial for diagnosis and follow-up. From the review of the literature, it was evident that the imaging techniques used involved the evaluation of only the thoracic findings, in particular the heart and the thoracic aorta, while no data are currently available on the distal abdominal aorta or iliac arteries, since ultrasound and MRI are interrupted at the diaphragmatic level.

Eligibility

Primary outcome measure(s)

• Vascular and cardiac anomalies — 5 years
  description of the main cardiovascular anomalies found by MRI at the thoracic and abdominal level anomalies in terms of supernumeray arteries and/or veins and measurement of length and diameters of main vascular tracts (e.g. ascending, descending aorta, aortic arch, renal arteries...) or vascular congenital abnormalities

Trial sites (1)

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