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Clinical Trials in Italy / NCT05876390
Enrolling by invitation Observational

Impact of Regional Anesthesia on Chronic Post-operative Pain

NCT05876390 · tracked via the Priya Life Science Italy tracker
Sponsor
Niguarda Hospital
Phase
Observational
Started
2022-09-01
Last updated
2026-04-16

Condition(s) studied

Breast Cancer

Investigational drug(s) / intervention(s)

Breast surgeryanalgesia →

Breast surgery: Breast surgery

analgesia: Multimodal analgesia

Study summary

Approximately 55,000 cases of breast cancer are diagnosed in Italy every year and the first-line therapy for carcinoma in situ, stage I, II and IIIA is surgical removal of the tumour. The incidence of chronic pain after breast cancer surgery is confirmed around 30%. This study aims to evaluate the impact of loco-regional anesthesia techniques in the context of multimodal analgesia in the prevention of chronic pain post-oncological breast surgery

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion criteria * Age \> 18 * Oncological breast surgery: * simple mastectomy, * mastectomy + sentinel lymph node biopsy, * mastectomy + axillary hollowing, * mastectomy + reconstruction, * simple quadrantectomy, * quadrantectomy + sentinel lymph node biopsy, * quadrantectomy + axillary hollowing, * bilateral interventions will also be considered) Exclusion * Age \< 18

Primary outcome measure(s)

  • Incidence of chronic postoperative pain after major breast surgery — 6 - 12 months
    Incidence of chronic post-surgical pain after major breast surgery (definition: pain that persists at least 3 months after surgery; pain that was not present before surgery or that has different characteristics from pain before surgery or that has increased intensity than before the operation; the pain is localized in the area of the surgical site or in its radiation; other possible causes of pain are excluded)

Trial sites (1)

FacilityCityRegionStatus
ASST GOM Niguarda Milan Lombardy

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Other trials for the same condition

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study A) Active, not recruiting
The OPBC-07/microNAC Study Active, not recruiting
Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2) Recruiting
Vocational Rehabilitation for the Return to Work of Breast Cancer Patients: a Feasibility Study Active, not recruiting
Music Therapy in Patients With Breast Cancer (IMPACT) Enrolling by invitation
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05876390 on ClinicalTrials.gov ↗ ← All trials in Italy