Endoscopic Resection of Gastrointestinal Neoplasms

Condition(s) studied

Investigational drug(s) / intervention(s)

Endoscopic resection: The endoscopic resection is the procedure that allows to remove cancerous or precancerous conditions of digestive tract. Endoscopic resection can be preformed by several techniques: 1. Endoscopic mucosal resection (EMR): it allows to remove mucosal lesions 2. Endoscopic submucosal dissection: it allows to remove mucosal lesions that involved submucosal layer and large lesions 3. Full-thickness resection: it allows to remove infiltrating lesions by the resection of a little piece of the entire gastrointestinal wall

Study summary

The study aims to retrospectively investigate the endoscopic resection procedures of cancerous and precancerous lesions of the upper and lower digestive tract in order to evaluate the efficacy and safety outcomes and to compare different resection techniques. In particular, the resection techniques investigated will be mucosectomy, en bloc and piecemeal, endoscopic submucosal dissection (ESD) and its variants, full-thickness resection. The anatomical districts involved will be the esophagus, stomach, duodenum, colon and rectum.

Eligibility

Primary outcome measure(s)

• en bloc resection rate — one month
  the en bloc resection is the ability to remove the neoplasia in a single piece
• complete resection rate — one month
  the complete resection is the ability to remove the neoplasia with clear margins (R0)
• recurrence rate — one year
  recurrence is the recurrence of the neoplasm at the resection site during follow-up

Trial sites (1)

More Azienda USL Reggio Emilia - IRCCS trials in Italy

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