Clinical Trials in Israel / NCT05697874
Recruiting
Observational
International Rare Brain Tumor Registry
NCT05697874 · tracked via the Priya Life Science Israel tracker
Condition(s) studied
AstroblastomaBCOR ITD SarcomaCNS SarcomaUnclassified Tumor, Malignant
Study summary
The objective of the International Rare Brain Tumor Registry (IRBTR) is to better understand rare brain tumors through the collection of biospecimens and matched clinical data of children, adolescents, and young adult patients diagnosed with rare brain tumors.
Eligibility
Inclusion Criteria:
* Patients with a known or suspected CNS Sarcoma.
* Patients with a known or suspected BCOR-altered brain tumor
* Patients with a known or suspected Astroblastoma/NM-1 altered brain tumor
* Patients with known or suspected histologically ambiguous/unclassifiable brain tumor
* Patients with a known or suspected rare brain tumor.
* Signed informed consent by patient/ parent or guardian (assent where applicable) to participate in the study.
Exclusion Criteria:
* The patient has an extra-CNS primary tumor.
* The patient is older than 46 years of age at diagnosis.
* The patient or family is not willing to participate or does not sign informed consent.
Primary outcome measure(s)
- Event-free Survival — 10 years
The primary outcome measure will be time from diagnosis to an event, defined as the occurrence of progression or recurrence of the disease, occurrence of a second malignant neoplasm, or death from any cause. Each cohort will be analyzed separately.
Trial sites (13)
| Facility | City | Region | Status |
|---|---|---|---|
| Children's Hospital Los Angeles | Los Angeles | California | Recruiting |
| University of California San Francisco | San Francisco | California | Recruiting |
| Children's National Hospital | Washington D.C. | District of Columbia | Recruiting |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago | Illinois | Recruiting |
| Akron Children's Hospital | Akron | Ohio | Recruiting |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | Recruiting |
| TUCCA - Santa Marcelina | São Paulo | São Paulo | Recruiting |
| HOMI - Fundación Hospital de la Misericordia | Bogotá | Bogota D.C. | Recruiting |
| Clinica Del Country | Bogotá | Colombia | Recruiting |
| Rambam Health Care Campus | Haifa | Israel | Recruiting |
| Schneider Children's Medical Center- CLALIT Health Services | Petah Tikva | Israel | Recruiting |
| Dana-Dwek Children's Hospital- Tel Aviv Medical Center | Tel Aviv | Israel | Recruiting |
| The Sheba Medical Center | Tel HaShomer | Israel | Recruiting |
Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT05697874 on ClinicalTrials.gov ↗ ← All trials in Israel